Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54973
MIM: 611354
HGNC: 26052
Ensembl: ENSG00000127054
Variants:
dbSNP: 54973
ClinVar: 54973
TCGA: ENSG00000127054
COSMIC: INTS11
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Gene Expression | REACTOME | R-HSA-74160 |
| RNA polymerase II transcribes snRNA genes | REACTOME | R-HSA-6807505 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36822327 | 2023 | An examination of the metal ion content in the active sites of human endonucleases CPSF73 and INTS11. | 2 |
| 37980560 | 2023 | A homozygous variant in INTS11 links mitosis and neurogenesis defects to a severe neurodevelopmental disorder. | 0 |
| 36822327 | 2023 | An examination of the metal ion content in the active sites of human endonucleases CPSF73 and INTS11. | 2 |
| 37980560 | 2023 | A homozygous variant in INTS11 links mitosis and neurogenesis defects to a severe neurodevelopmental disorder. | 0 |
| 34551776 | 2021 | NACK and INTEGRATOR act coordinately to activate Notch-mediated transcription in tumorigenesis. | 5 |
| 34551776 | 2021 | NACK and INTEGRATOR act coordinately to activate Notch-mediated transcription in tumorigenesis. | 5 |
| 29471365 | 2018 | Integrator subunit 4 is a 'Symplekin-like' scaffold that associates with INTS9/11 to form the Integrator cleavage module. | 43 |
| 29471365 | 2018 | Integrator subunit 4 is a 'Symplekin-like' scaffold that associates with INTS9/11 to form the Integrator cleavage module. | 43 |
| 28396433 | 2017 | Molecular basis for the interaction between Integrator subunits IntS9 and IntS11 and its functional importance. | 40 |
| 28396433 | 2017 | Molecular basis for the interaction between Integrator subunits IntS9 and IntS11 and its functional importance. | 40 |
| 22252320 | 2012 | snRNA 3' end formation requires heterodimeric association of integrator subunits. | 43 |
| 22252320 | 2012 | snRNA 3' end formation requires heterodimeric association of integrator subunits. | 43 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 20628086 | 2010 | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. | 15 |
| 19913121 | 2009 | Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. | 105 |
Citation
Dessen P
INTS11 (integrator complex subunit 11)
Atlas Genet Cytogenet Oncol Haematol. 2017-09-01
Online version: http://atlasgeneticsoncology.org/gene/79300/ints11-(integrator-complex-subunit-11)
