MINDY2 (MINDY lysine 48 deubiquitinase 2)

2017-09-01  

Identity

HGNC
MINDY2
LOCATION
15q21.3
LOCUSID
54629
ALIAS
FAM63B

Other Information

Locus ID:

NCBI: 54629
MIM: 618408
HGNC: 26954
Ensembl: ENSG00000128923

Variants:

dbSNP: 54629
ClinVar: 54629
TCGA: ENSG00000128923
COSMIC: MINDY2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000128923ENST00000316848J3KNL7
ENSG00000128923ENST00000450403Q8NBR6
ENSG00000128923ENST00000559228Q8NBR6
ENSG00000128923ENST00000560289H0YM15

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
381518242024Exosomal circFAM63Bsuppresses bone regeneration of postmenopausal osteoporosis via regulating miR-578/HMGA2 axis.1
381518242024Exosomal circFAM63Bsuppresses bone regeneration of postmenopausal osteoporosis via regulating miR-578/HMGA2 axis.1
345299272021Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2.9
345299272021Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2.9
271752192016Hypomethylation of FAM63B in bipolar disorder patients.7
271752192016Hypomethylation of FAM63B in bipolar disorder patients.7

Citation

Dessen P

MINDY2 (MINDY lysine 48 deubiquitinase 2)

Atlas Genet Cytogenet Oncol Haematol. 2017-09-01

Online version: http://atlasgeneticsoncology.org/gene/79477/mindy2-(mindy-lysine-48-deubiquitinase-2)