NEXMIF (neurite extension and migration factor)

2017-09-01  

Identity

HGNC
LOCATION
Xq13.3
LOCUSID
ALIAS
KIAA2022,KIDLIA,MRX98,XPN

Other Information

Locus ID:

NCBI: 340533
MIM: 300524
HGNC: 29433
Ensembl: ENSG00000050030

Variants:

dbSNP: 340533
ClinVar: 340533
TCGA: ENSG00000050030
COSMIC: NEXMIF

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000050030ENST00000055682Q5QGS0
ENSG00000050030ENST00000424929H7C2N8
ENSG00000050030ENST00000616200Q5QGS0
ENSG00000050030ENST00000642681A0A2R8YEQ5

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
343265012022Clinical evaluation of torpedo maculopathy in an infant population with additional genetic testing for NEXMIF mutation.0
351469032022NEXMIF pathogenic variants in individuals of Korean, Vietnamese, and Mexican descent.1
355454182022NEXMIF mutations in intellectual disability and epilepsy: A report of 2 cases and literature review.0
361700932022[Epilepsy and other phenotypic features of X-linked intellectual disability caused by the mutations in the KIAA2022 gene].0
343265012022Clinical evaluation of torpedo maculopathy in an infant population with additional genetic testing for NEXMIF mutation.0
351469032022NEXMIF pathogenic variants in individuals of Korean, Vietnamese, and Mexican descent.1
355454182022NEXMIF mutations in intellectual disability and epilepsy: A report of 2 cases and literature review.0
361700932022[Epilepsy and other phenotypic features of X-linked intellectual disability caused by the mutations in the KIAA2022 gene].0
331446812021NEXMIF encephalopathy: an X-linked disorder with male and female phenotypic patterns.17
331446812021NEXMIF encephalopathy: an X-linked disorder with male and female phenotypic patterns.17
326008412020Clinical spectrum of KIAA2022/NEXMIF pathogenic variants in males and females: Report of three patients from Indian kindred with a review of published patients.4
326008412020Clinical spectrum of KIAA2022/NEXMIF pathogenic variants in males and females: Report of three patients from Indian kindred with a review of published patients.4
296937852018Clinical spectrum of KIAA2022 pathogenic variants in males: Case report of two boys with KIAA2022 pathogenic variants and review of the literature.11
297171862018Novel NEXMIF pathogenic variant in a boy with severe autistic features, intellectual disability, and epilepsy, and his mildly affected mother.9
296937852018Clinical spectrum of KIAA2022 pathogenic variants in males: Case report of two boys with KIAA2022 pathogenic variants and review of the literature.11

Citation

Dessen P

NEXMIF (neurite extension and migration factor)

Atlas Genet Cytogenet Oncol Haematol. 2017-09-01

Online version: http://atlasgeneticsoncology.org/gene/79981/nexmif-(neurite-extension-and-migration-factor)