ATP5MF (ATP synthase membrane subunit f)

2018-11-01  

Identity

HGNC
ATP5MF
LOCATION
7q22.1
LOCUSID
9551
ALIAS
ATP5J2,ATP5JL

Other Information

Locus ID:

NCBI: 9551
HGNC: 848
Ensembl: ENSG00000241468

Variants:

dbSNP: 9551
ClinVar: 9551
TCGA: ENSG00000241468
COSMIC: ATP5MF

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000241468ENST00000292475P56134
ENSG00000241468ENST00000359832P56134
ENSG00000241468ENST00000394186P56134
ENSG00000241468ENST00000414062P56134
ENSG00000241468ENST00000449683C9JU26
ENSG00000241468ENST00000488775P56134
ENSG00000241468ENST00000523680E5RKA0

Pathways

PathwaySourceExternal ID
Oxidative phosphorylationKEGGko00190
Oxidative phosphorylationKEGGhsa00190
Metabolic pathwaysKEGGhsa01100
F-type ATPase, eukaryotesKEGGhsa_M00158
F-type ATPase, eukaryotesKEGGM00158
MetabolismREACTOMER-HSA-1430728
The citric acid (TCA) cycle and respiratory electron transportREACTOMER-HSA-1428517
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.REACTOMER-HSA-163200
Formation of ATP by chemiosmotic couplingREACTOMER-HSA-163210

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
339294902021The F1Fo-ATPase inhibitor, IF1, is a critical regulator of energy metabolism in cancer cells.6
339294902021The F1Fo-ATPase inhibitor, IF1, is a critical regulator of energy metabolism in cancer cells.6
326534532020The new role of F(1)F(o) ATP synthase in mitochondria-mediated neurodegeneration and neuroprotection.15
326534532020The new role of F(1)F(o) ATP synthase in mitochondria-mediated neurodegeneration and neuroprotection.15
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
190645712008Polymorphisms in mitochondrial genes and prostate cancer risk.22
190645712008Polymorphisms in mitochondrial genes and prostate cancer risk.22

Citation

Dessen P

ATP5MF (ATP synthase membrane subunit f)

Atlas Genet Cytogenet Oncol Haematol. 2018-11-01

Online version: http://atlasgeneticsoncology.org/gene/80328/atp5mf-(atp-synthase-membrane-subunit-f)