TENT2 (terminal nucleotidyltransferase 2)

2018-11-01  

Identity

HGNC
LOCATION
5q14.1
LOCUSID
ALIAS
APD4,GLD2,PAPD4,TUT2

Other Information

Locus ID:

NCBI: 167153
MIM: 614121
HGNC: 26776
Ensembl: ENSG00000164329

Variants:

dbSNP: 167153
ClinVar: 167153
TCGA: ENSG00000164329
COSMIC: TENT2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164329ENST00000296783Q6PIY7
ENSG00000164329ENST00000423041Q6PIY7
ENSG00000164329ENST00000428308Q6PIY7
ENSG00000164329ENST00000453514Q6PIY7
ENSG00000164329ENST00000504233D6RAF2

References

Pubmed IDYearTitleCitations
360710582022TENT2, TUT4, and TUT7 selectively regulate miRNA sequence and abundance.17
360710582022TENT2, TUT4, and TUT7 selectively regulate miRNA sequence and abundance.17
337563492021DDX6 is a positive regulator of Ataxin-2/PAPD4 cytoplasmic polyadenylation machinery.1
337563492021DDX6 is a positive regulator of Ataxin-2/PAPD4 cytoplasmic polyadenylation machinery.1
317920532020The RNA-binding protein QKI-7 recruits the poly(A) polymerase GLD-2 for 3' adenylation and selective stabilization of microRNA-122.15
317920532020The RNA-binding protein QKI-7 recruits the poly(A) polymerase GLD-2 for 3' adenylation and selective stabilization of microRNA-122.15
310570872019Gld2 activity is regulated by phosphorylation in the N-terminal domain.6
310570872019Gld2 activity is regulated by phosphorylation in the N-terminal domain.6
269261062016The STAR protein QKI-7 recruits PAPD4 to regulate post-transcriptional polyadenylation of target mRNAs.22
273669062016Hepatitis C Virus Core Protein Promotes miR-122 Destabilization by Inhibiting GLD-2.18
269261062016The STAR protein QKI-7 recruits PAPD4 to regulate post-transcriptional polyadenylation of target mRNAs.22
273669062016Hepatitis C Virus Core Protein Promotes miR-122 Destabilization by Inhibiting GLD-2.18
246673242014HBx down-regulated Gld2 plays a critical role in HBV-related dysregulation of miR-122.26
246673242014HBx down-regulated Gld2 plays a critical role in HBV-related dysregulation of miR-122.26
227276652012Bidirectional control of mRNA translation and synaptic plasticity by the cytoplasmic polyadenylation complex.82

Citation

Dessen P

TENT2 (terminal nucleotidyltransferase 2)

Atlas Genet Cytogenet Oncol Haematol. 2018-11-01

Online version: http://atlasgeneticsoncology.org/gene/80489/tent2-(terminal-nucleotidyltransferase-2)