Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9980
MIM: 604803
HGNC: 1291
Ensembl: ENSG00000142197
Variants:
dbSNP: 9980
ClinVar: 9980
TCGA: ENSG00000142197
COSMIC: DOP1B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000142197 | ENST00000270190 | F8W8U9 |
| ENSG00000142197 | ENST00000399151 | Q9Y3R5 |
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA443560 | Breast Neoplasms | Disease | VariantAnnotation | not associated | PD | 29938344 | |
| PA449165 | cyclophosphamide | Chemical | VariantAnnotation | not associated | PD | 29938344 | |
| PA449412 | doxorubicin | Chemical | VariantAnnotation | not associated | PD | 29938344 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33273802 | 2020 | A mutation in DOP1B identified as a probable cause for autosomal recessive Peters anomaly in a consanguineous family. | 0 |
| 33273802 | 2020 | A mutation in DOP1B identified as a probable cause for autosomal recessive Peters anomaly in a consanguineous family. | 0 |
| 30213940 | 2018 | SNX3-retromer requires an evolutionary conserved MON2:DOPEY2:ATP9A complex to mediate Wntless sorting and Wnt secretion. | 37 |
| 30213940 | 2018 | SNX3-retromer requires an evolutionary conserved MON2:DOPEY2:ATP9A complex to mediate Wntless sorting and Wnt secretion. | 37 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 19460634 | 2009 | A quantitative assessment of gene expression (QAGE) reveals differential overexpression of DOPEY2, a candidate gene for mental retardation, in Down syndrome brain regions. | 14 |
| 19460634 | 2009 | A quantitative assessment of gene expression (QAGE) reveals differential overexpression of DOPEY2, a candidate gene for mental retardation, in Down syndrome brain regions. | 14 |
| 16276086 | 2006 | C21orf5, a human candidate gene for brain abnormalities and mental retardation in Down syndrome. | 6 |
| 16276086 | 2006 | C21orf5, a human candidate gene for brain abnormalities and mental retardation in Down syndrome. | 6 |
| 16303751 | 2005 | C21orf5, a new member of Dopey family involved in morphogenesis, could participate in neurological alterations and mental retardation in Down syndrome. | 8 |
| 16303751 | 2005 | C21orf5, a new member of Dopey family involved in morphogenesis, could participate in neurological alterations and mental retardation in Down syndrome. | 8 |
| 12767918 | 2003 | The differentially expressed C21orf5 gene in the medial temporal-lobe system could play a role in mental retardation in Down syndrome and transgenic mice. | 5 |
| 12767918 | 2003 | The differentially expressed C21orf5 gene in the medial temporal-lobe system could play a role in mental retardation in Down syndrome and transgenic mice. | 5 |
Citation
Dessen P
DOP1B (DOP1 leucine zipper like protein B)
Atlas Genet Cytogenet Oncol Haematol. 2018-11-01
Online version: http://atlasgeneticsoncology.org/gene/80507/dop1b-(dop1-leucine-zipper-like-protein-b)
