Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23517
MIM: 618122
HGNC: 18734
Ensembl: ENSG00000039123
Variants:
dbSNP: 23517
ClinVar: 23517
TCGA: ENSG00000039123
COSMIC: MTREX
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000039123 | ENST00000230640 | P42285 |
| ENSG00000039123 | ENST00000505565 | H0Y8U3 |
| ENSG00000039123 | ENST00000506750 | D6REC7 |
| ENSG00000039123 | ENST00000508716 | H0YAC4 |
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36929008 | 2023 | RNA helicase MTR4 drives tumorigenesis of nasopharyngeal carcinoma by regulating the expression of key cell cycle genes. | 0 |
| 36929008 | 2023 | RNA helicase MTR4 drives tumorigenesis of nasopharyngeal carcinoma by regulating the expression of key cell cycle genes. | 0 |
| 36403484 | 2022 | MTR4 adaptor PICT1 functions in two distinct steps during pre-rRNA processing. | 0 |
| 36403484 | 2022 | MTR4 adaptor PICT1 functions in two distinct steps during pre-rRNA processing. | 0 |
| 33422691 | 2021 | Interactome analysis of the Tudor domain-containing protein SPF30 which associates with the MTR4-exosome RNA-decay machinery under the regulation of AAA-ATPase NVL2. | 2 |
| 33857361 | 2021 | Mtr4 RNA helicase structures and interactions. | 6 |
| 33422691 | 2021 | Interactome analysis of the Tudor domain-containing protein SPF30 which associates with the MTR4-exosome RNA-decay machinery under the regulation of AAA-ATPase NVL2. | 2 |
| 33857361 | 2021 | Mtr4 RNA helicase structures and interactions. | 6 |
| 32024842 | 2020 | MTR4 drives liver tumorigenesis by promoting cancer metabolic switch through alternative splicing. | 45 |
| 32350160 | 2020 | Exploration of Salmonella effector mutant strains on MTR4 and RRP6 degradation. | 3 |
| 32463452 | 2020 | Mapping domains of ARS2 critical for its RNA decay capacity. | 8 |
| 32024842 | 2020 | MTR4 drives liver tumorigenesis by promoting cancer metabolic switch through alternative splicing. | 45 |
| 32350160 | 2020 | Exploration of Salmonella effector mutant strains on MTR4 and RRP6 degradation. | 3 |
| 32463452 | 2020 | Mapping domains of ARS2 critical for its RNA decay capacity. | 8 |
| 30842217 | 2019 | NRDE2 negatively regulates exosome functions by inhibiting MTR4 recruitment and exosome interaction. | 24 |
Citation
Dessen P
MTREX (Mtr4 exosome RNA helicase)
Atlas Genet Cytogenet Oncol Haematol. 2018-11-01
Online version: http://atlasgeneticsoncology.org/gene/80523/mtrex-(mtr4-exosome-rna-helicase)
