BMP5 (bone morphogenetic protein 5)

2003-05-01  

Identity

HGNC
BMP5
LOCATION
6p12.1
LOCUSID
653
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 653
MIM: 112265
HGNC: 1072
Ensembl: ENSG00000112175

Variants:

dbSNP: 653
ClinVar: 653
TCGA: ENSG00000112175
COSMIC: BMP5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000112175ENST00000370830P22003
ENSG00000112175ENST00000370830M9VUD0

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
TGF-beta signaling pathwayKEGGko04350
TGF-beta signaling pathwayKEGGhsa04350
Hippo signaling pathwayKEGGhsa04390
Hippo signaling pathwayKEGGko04390
BMP signalingKEGGhsa_M00679
BMP signalingKEGGM00679

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA10074escitalopramChemicalClinicalAnnotationassociatedPD23926243
PA447321Depressive Disorder, MajorDiseaseClinicalAnnotationassociatedPD23926243

References

Pubmed IDYearTitleCitations
350547762022G9a Knockdown Suppresses Cancer Aggressiveness by Facilitating Smad Protein Phosphorylation through Increasing BMP5 Expression in Luminal A Type Breast Cancer.7
350547762022G9a Knockdown Suppresses Cancer Aggressiveness by Facilitating Smad Protein Phosphorylation through Increasing BMP5 Expression in Luminal A Type Breast Cancer.7
329680942020Detection of circulating BMP5 as a risk factor for Barrett's esophagus.0
329680942020Detection of circulating BMP5 as a risk factor for Barrett's esophagus.0
301191702018MiR-32 promotes tumorigenesis of colorectal cancer by targeting BMP5.20
305728832018Alteration of tumor suppressor BMP5 in sporadic colorectal cancer: a genomic and transcriptomic profiling based study.26
301191702018MiR-32 promotes tumorigenesis of colorectal cancer by targeting BMP5.20
305728832018Alteration of tumor suppressor BMP5 in sporadic colorectal cancer: a genomic and transcriptomic profiling based study.26
286958692017Evaluation of the association between a single-nucleotide polymorphism of bone morphogenetic proteins 5 gene and risk of knee osteoarthritis.1
286958692017Evaluation of the association between a single-nucleotide polymorphism of bone morphogenetic proteins 5 gene and risk of knee osteoarthritis.1
259940082015Differential expression of bone morphogenetic protein 5 in human lung squamous cell carcinoma and adenocarcinoma.14
259940082015Differential expression of bone morphogenetic protein 5 in human lung squamous cell carcinoma and adenocarcinoma.14
243844272014Genome-wide study reveals an important role of spontaneous autoimmunity, cardiomyocyte differentiation defect and anti-angiogenic activities in gender-specific gene expression in Keshan disease.5
245512732014Expression analysis of BMP2, BMP5, BMP10 in human colon tissues from Hirschsprung disease patients.3
250304052014Association between single nucleotide polymorphisms of asporin (ASPN) and BMP5 with the risk of knee osteoarthritis in a Chinese Han population.9

Citation

Dessen P

BMP5 (bone morphogenetic protein 5)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/812/bmp5-(bone-morphogenetic-protein-5)