BMP7 (bone morphogenetic protein 7)

2003-12-01  

Identity

HGNC
BMP7
LOCATION
20q13.31
LOCUSID
655
ALIAS
OP-1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 655
MIM: 112267
HGNC: 1074
Ensembl: ENSG00000101144

Variants:

dbSNP: 655
ClinVar: 655
TCGA: ENSG00000101144
COSMIC: BMP7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000101144ENST00000395863P18075
ENSG00000101144ENST00000395863A8K571
ENSG00000101144ENST00000395864B1AKZ9
ENSG00000101144ENST00000433911H0Y4B5
ENSG00000101144ENST00000450594B1AL00

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Cytokine-cytokine receptor interactionKEGGko04060
TGF-beta signaling pathwayKEGGko04350
Axon guidanceKEGGko04360
Cytokine-cytokine receptor interactionKEGGhsa04060
TGF-beta signaling pathwayKEGGhsa04350
Axon guidanceKEGGhsa04360
Hippo signaling pathwayKEGGhsa04390
Hippo signaling pathwayKEGGko04390
BMP signalingKEGGhsa_M00679
BMP signalingKEGGM00679
Extracellular matrix organizationREACTOMER-HSA-1474244
Elastic fibre formationREACTOMER-HSA-1566948
Molecules associated with elastic fibresREACTOMER-HSA-2129379

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA164760860pegaspargaseChemicalClinicalAnnotationassociatedPD26590194
PA445187OsteonecrosisDiseaseClinicalAnnotationassociatedPD26590194
PA446155Precursor Cell Lymphoblastic Leukemia-LymphomaDiseaseClinicalAnnotationassociatedPD26590194
PA449165cyclophosphamideChemicalClinicalAnnotationassociatedPD26590194
PA449177cytarabineChemicalClinicalAnnotationassociatedPD26590194
PA449212daunorubicinChemicalClinicalAnnotationassociatedPD26590194
PA449247dexamethasoneChemicalClinicalAnnotationassociatedPD26590194
PA449412doxorubicinChemicalClinicalAnnotationassociatedPD26590194
PA450428methotrexateChemicalClinicalAnnotationassociatedPD26590194
PA451100prednisoneChemicalClinicalAnnotationassociatedPD26590194
PA451663thioguanineChemicalClinicalAnnotationassociatedPD26590194
PA451879vincristineChemicalClinicalAnnotationassociatedPD26590194

References

Pubmed IDYearTitleCitations
373004832024BMP7 expression in mammalian cortical radial glial cells increases the length of the neurogenic period.2
382596702024SCUBE1 promotes pulmonary artery smooth muscle cell proliferation and migration in acute pulmonary embolism by modulating BMP7.0
387536412024Impact of Bone Morphogenetic Protein 7 and Prostaglandin receptors on osteoblast healing and organization of collagen.0
373004832024BMP7 expression in mammalian cortical radial glial cells increases the length of the neurogenic period.2
382596702024SCUBE1 promotes pulmonary artery smooth muscle cell proliferation and migration in acute pulmonary embolism by modulating BMP7.0
387536412024Impact of Bone Morphogenetic Protein 7 and Prostaglandin receptors on osteoblast healing and organization of collagen.0
367651432023Conserved miR-370-3p/BMP-7 axis regulates the phenotypic change of human vascular smooth muscle cells.0
376883742023High BMP7 expression is associated with poor prognosis in ovarian cancer.1
367651432023Conserved miR-370-3p/BMP-7 axis regulates the phenotypic change of human vascular smooth muscle cells.0
376883742023High BMP7 expression is associated with poor prognosis in ovarian cancer.1
350331262022Immunohistochemical analysis revealed the expression of bone morphogenetic proteins-4, 6, 7, and 9 in human induced membrane samples treated with the Masquelet technique.1
350889572022[Evaluation of Annexin-1 (ANXA-1), Annexin-2 (ANXA-2) and Bone Morphogenetic Protein-7 (BMP-7) Serum Levels in Patients Followed Up With A Diagnosis of COVID-19].5
351391062022BMP7 increases protein synthesis in SW1353 cells and determines rRNA levels in a NKX3-2-dependent manner.0
353310812022Lysine (K)-specific demethylase 5C regulates the incidence of severe preeclampsia by adjusting the expression of bone morphogenetic protein-7.0
356710492022Potential Therapeutic Role of Bone Morphogenic Protein 7 (BMP7) in the Pathogenesis of Graves' Orbitopathy.3

Citation

Dessen P

BMP7 (bone morphogenetic protein 7)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/814/bmp7-(bone-morphogenetic-protein-7)