BSG (basigin (Ok blood group))

2003-06-01  

Identity

HGNC
LOCATION
19p13.3
LOCUSID
ALIAS
5F7,CD147,EMMPRIN,EMPRIN,HAb18G,OK,SLC7A11,TCSF
FUSION GENES

Other Information

Locus ID:

NCBI: 682
MIM: 109480
HGNC: 1116
Ensembl: ENSG00000172270

Variants:

dbSNP: 682
ClinVar: 682
TCGA: ENSG00000172270
COSMIC: BSG

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000172270ENST00000333511P35613
ENSG00000172270ENST00000346916P35613
ENSG00000172270ENST00000353555P35613
ENSG00000172270ENST00000353555Q54A51
ENSG00000172270ENST00000545507P35613
ENSG00000172270ENST00000573216I3L192
ENSG00000172270ENST00000573784R4GMX5
ENSG00000172270ENST00000576984R4GN83
ENSG00000172270ENST00000613627A0A087X2B5
ENSG00000172270ENST00000614867A0A087X215
ENSG00000172270ENST00000618006A0A087WUV8
ENSG00000172270ENST00000618112A0A2R8YDZ0

Expression (GTEx)

0
100
200
300
400
500
600
700
800
900

Pathways

PathwaySourceExternal ID
HemostasisREACTOMER-HSA-109582
Cell surface interactions at the vascular wallREACTOMER-HSA-202733
Basigin interactionsREACTOMER-HSA-210991
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsREACTOMER-HSA-425366
Proton-coupled monocarboxylate transportREACTOMER-HSA-433692
MetabolismREACTOMER-HSA-1430728
The citric acid (TCA) cycle and respiratory electron transportREACTOMER-HSA-1428517
Pyruvate metabolism and Citric Acid (TCA) cycleREACTOMER-HSA-71406
Pyruvate metabolismREACTOMER-HSA-70268
Extracellular matrix organizationREACTOMER-HSA-1474244
Degradation of the extracellular matrixREACTOMER-HSA-1474228
Integrin cell surface interactionsREACTOMER-HSA-216083

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
379521052024CircCDK17 promotes the proliferation and metastasis of ovarian cancer cells by sponging miR-22-3p to regulate CD147 expression.0
380388522024CD147 Plasma Levels in Hospitalised Patients with Covid-19 Pneumonia Predict Illness Severity and In-Hospital Mortality.0
382878152024Potential Alternative Receptors for SARS-CoV-2-Induced Kidney Damage: TLR-4, KIM-1/TIM-1, and CD147.0
383181872024Soluble CD147 regulates endostatin via its effects on the activities of MMP-9 and secreted proteasome 20S.1
384843692024A comprehensive investigation on the receptor BSG expression reveals the potential risk of healthy individuals and cancer patients to 2019-nCoV infection.0
386175452024TIE1 promotes cervical cancer progression via Basigin-matrix metalloproteinase axis.0
386610402024MCT4 and CD147 colocalize with MMP14 in invadopodia and support matrix degradation and invasion by breast cancer cells.0
388920562024ADAM12-Generated Basigin Ectodomain Binds β1 Integrin and Enhances the Expression of Cancer-Related Extracellular Matrix Proteins.0
379521052024CircCDK17 promotes the proliferation and metastasis of ovarian cancer cells by sponging miR-22-3p to regulate CD147 expression.0
380388522024CD147 Plasma Levels in Hospitalised Patients with Covid-19 Pneumonia Predict Illness Severity and In-Hospital Mortality.0
382878152024Potential Alternative Receptors for SARS-CoV-2-Induced Kidney Damage: TLR-4, KIM-1/TIM-1, and CD147.0
383181872024Soluble CD147 regulates endostatin via its effects on the activities of MMP-9 and secreted proteasome 20S.1
384843692024A comprehensive investigation on the receptor BSG expression reveals the potential risk of healthy individuals and cancer patients to 2019-nCoV infection.0
386175452024TIE1 promotes cervical cancer progression via Basigin-matrix metalloproteinase axis.0
386610402024MCT4 and CD147 colocalize with MMP14 in invadopodia and support matrix degradation and invasion by breast cancer cells.0

Citation

Dessen P

BSG (basigin (Ok blood group))

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/845/bsg-(basigin-(ok-blood-group))