BTG2 (BTG anti-proliferation factor 2)

2003-02-01  

Identity

HGNC
BTG2
LOCATION
1q32.1
LOCUSID
7832
ALIAS
APRO1,PC3,TIS21
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 7832
MIM: 601597
HGNC: 1131
Ensembl: ENSG00000159388

Variants:

dbSNP: 7832
ClinVar: 7832
TCGA: ENSG00000159388
COSMIC: BTG2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000159388ENST00000290551P78543
ENSG00000159388ENST00000475157P78543

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
RNA degradationKEGGko03018
RNA degradationKEGGhsa03018
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
Transcriptional Regulation by TP53REACTOMER-HSA-3700989
TP53 Regulates Transcription of Cell Cycle GenesREACTOMER-HSA-6791312
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertainREACTOMER-HSA-6804115

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
383293432024MicroRNA-409-3p/BTG2 signaling axis improves impaired angiogenesis and wound healing in obese mice.0
387293252024SMC2 knockdown inhibits malignant progression of lung adenocarcinoma by upregulating BTG2 expression.0
388313222024Deciphering the molecular nexus of BTG2 in periodontitis and diabetic kidney disease.0
383293432024MicroRNA-409-3p/BTG2 signaling axis improves impaired angiogenesis and wound healing in obese mice.0
387293252024SMC2 knockdown inhibits malignant progression of lung adenocarcinoma by upregulating BTG2 expression.0
388313222024Deciphering the molecular nexus of BTG2 in periodontitis and diabetic kidney disease.0
352391482023Mir-25 Promotes Metastasis of Esophageal Cancer by Targeting BTG2.1
363143692023LncRNA CARMN inhibits cervical cancer cell growth via the miR-92a-3p/BTG2/Wnt/β-catenin axis.0
372572432023BTG2 suppresses the growth and metastasis of cervical squamous cell carcinoma.1
372695932023BTG2 acts as an inducer of muscle stem cell senescence.2
378949952023miR-103-3p Regulates the Proliferation and Differentiation of C2C12 Myoblasts by Targeting BTG2.0
352391482023Mir-25 Promotes Metastasis of Esophageal Cancer by Targeting BTG2.1
363143692023LncRNA CARMN inhibits cervical cancer cell growth via the miR-92a-3p/BTG2/Wnt/β-catenin axis.0
372572432023BTG2 suppresses the growth and metastasis of cervical squamous cell carcinoma.1
372695932023BTG2 acts as an inducer of muscle stem cell senescence.2

Citation

Dessen P

BTG2 (BTG anti-proliferation factor 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/848/btg2-(btg-anti-proliferation-factor-2)