SSX1 (SSX family member 1)

2003-02-01  

Identity

HGNC
LOCATION
Xp11.23
LOCUSID
ALIAS
CT5.1,SSRC
FUSION GENES

Other Information

Locus ID:

NCBI: 6756
MIM: 312820
HGNC: 11335
Ensembl: ENSG00000126752

Variants:

dbSNP: 6756
ClinVar: 6756
TCGA: ENSG00000126752
COSMIC: SSX1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000126752ENST00000376919Q16384

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Transcriptional misregulation in cancerKEGGko05202
Transcriptional misregulation in cancerKEGGhsa05202

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
295029552018The SS18-SSX Oncoprotein Hijacks KDM2B-PRC1.1 to Drive Synovial Sarcoma.57
298933032018Primary pulmonary synovial sarcoma: A reappraisal.15
295029552018The SS18-SSX Oncoprotein Hijacks KDM2B-PRC1.1 to Drive Synovial Sarcoma.57
298933032018Primary pulmonary synovial sarcoma: A reappraisal.15
286317092017[Cancer-testis genes in colon cancer].3
286317092017[Cancer-testis genes in colon cancer].3
269058122016The fusion protein SS18-SSX1 employs core Wnt pathway transcription factors to induce a partial Wnt signature in synovial sarcoma.20
269470172016The impact of chromosomal translocation locus and fusion oncogene coding sequence in synovial sarcomagenesis.26
275723152016Identification of SHCBP1 as a novel downstream target gene of SS18-SSX1 and its functional analysis in progression of synovial sarcoma.15
269058122016The fusion protein SS18-SSX1 employs core Wnt pathway transcription factors to induce a partial Wnt signature in synovial sarcoma.20
269470172016The impact of chromosomal translocation locus and fusion oncogene coding sequence in synovial sarcomagenesis.26
275723152016Identification of SHCBP1 as a novel downstream target gene of SS18-SSX1 and its functional analysis in progression of synovial sarcoma.15
259598792015Detection of Rare Variant of SS18-SSX1 Fusion Gene and Mutations of Important Cancer-Related Genes in Synovial Sarcoma of the Lip: Gene Analyses of a Case and Literature Review.3
259598792015Detection of Rare Variant of SS18-SSX1 Fusion Gene and Mutations of Important Cancer-Related Genes in Synovial Sarcoma of the Lip: Gene Analyses of a Case and Literature Review.3
237161142014Loss of SS18-SSX1 inhibits viability and induces apoptosis in synovial sarcoma.20

Citation

Dessen P

SSX1 (SSX family member 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/87/ssx1