Identity
HGNC
LOCATION
11q12.1
LOCUSID
ALIAS
CANP,POIKTMP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 374393
MIM: 615584
HGNC: 24200
Ensembl: ENSG00000189057
Variants:
dbSNP: 374393
ClinVar: 374393
TCGA: ENSG00000189057
COSMIC: FAM111B
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37672204 | 2024 | Overexpressed FAM111B degrades GSDMA to promote esophageal cancer tumorigenesis and cisplatin resistance. | 1 |
| 37782700 | 2024 | Family with sequence similarity 111 member B contributes to tumor growth and metastasis by mediating cell proliferation, invasion, and EMT via transforming acidic coiled-coil protein 3/PI3K/AKT signaling pathway in hepatocellular carcinoma. | 1 |
| 38474092 | 2024 | Unravelling the Intricate Roles of FAM111A and FAM111B: From Protease-Mediated Cellular Processes to Disease Implications. | 0 |
| 37672204 | 2024 | Overexpressed FAM111B degrades GSDMA to promote esophageal cancer tumorigenesis and cisplatin resistance. | 1 |
| 37782700 | 2024 | Family with sequence similarity 111 member B contributes to tumor growth and metastasis by mediating cell proliferation, invasion, and EMT via transforming acidic coiled-coil protein 3/PI3K/AKT signaling pathway in hepatocellular carcinoma. | 1 |
| 38474092 | 2024 | Unravelling the Intricate Roles of FAM111A and FAM111B: From Protease-Mediated Cellular Processes to Disease Implications. | 0 |
| 36610347 | 2023 | FAM111B dysregulation promotes malignancy in fibrosarcoma and POIKTMP and a low-cost method for its mutation screening. | 2 |
| 37095701 | 2023 | Silencing of FAM111B inhibits tumor growth and promotes apoptosis by decreasing AKT activity in ovarian cancer. | 1 |
| 37270349 | 2023 | Silencing of FAM111B inhibited proliferation, migration and invasion of hepatoma cells through activating p53 pathway. | 1 |
| 36610347 | 2023 | FAM111B dysregulation promotes malignancy in fibrosarcoma and POIKTMP and a low-cost method for its mutation screening. | 2 |
| 37095701 | 2023 | Silencing of FAM111B inhibits tumor growth and promotes apoptosis by decreasing AKT activity in ovarian cancer. | 1 |
| 37270349 | 2023 | Silencing of FAM111B inhibited proliferation, migration and invasion of hepatoma cells through activating p53 pathway. | 1 |
| 34802969 | 2022 | YY1-Induced Transcriptional Activation of FAM111B Contributes to the Malignancy of Breast Cancer. | 8 |
| 35122327 | 2022 | Mutations within the putative protease domain of the human FAM111B gene may predict disease severity and poor prognosis: A review of POIKTMP cases. | 9 |
| 35864964 | 2022 | DNMT3B-mediated FAM111B methylation promotes papillary thyroid tumor glycolysis, growth and metastasis. | 9 |
Citation
Dessen P
FAM111B (FAM111 trypsin like peptidase B)
Atlas Genet Cytogenet Oncol Haematol. 2003-12-01
Online version: http://atlasgeneticsoncology.org/gene/909/fam111b-(fam111-trypsin-like-peptidase-b)
