Identity
HGNC
LOCATION
1p36.13
LOCUSID
ALIAS
CAPB,CAPPB,CAPZ
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 832
MIM: 601572
HGNC: 1491
Ensembl: ENSG00000077549
Variants:
dbSNP: 832
ClinVar: 832
TCGA: ENSG00000077549
COSMIC: CAPZB
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Endocytosis | KEGG | ko04144 |
| Endocytosis | KEGG | hsa04144 |
| Hemostasis | REACTOME | R-HSA-109582 |
| Factors involved in megakaryocyte development and platelet production | REACTOME | R-HSA-983231 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33564074 | 2021 | Vacuolin-1 inhibits endosomal trafficking and metastasis via CapZβ. | 14 |
| 34796874 | 2021 | Capping protein regulates endosomal trafficking by controlling F-actin density around endocytic vesicles and recruiting RAB5 effectors. | 7 |
| 33564074 | 2021 | Vacuolin-1 inhibits endosomal trafficking and metastasis via CapZβ. | 14 |
| 34796874 | 2021 | Capping protein regulates endosomal trafficking by controlling F-actin density around endocytic vesicles and recruiting RAB5 effectors. | 7 |
| 32170730 | 2020 | A new 1p36.13-1p36.12 microdeletion syndrome characterized by learning disability, behavioral abnormalities, and ptosis. | 4 |
| 32170730 | 2020 | A new 1p36.13-1p36.12 microdeletion syndrome characterized by learning disability, behavioral abnormalities, and ptosis. | 4 |
| 28104696 | 2017 | Systematic characterization of human testis-specific actin capping protein β3 as a possible biomarker for male infertility. | 6 |
| 28727628 | 2017 | Replication confirms the association of loci in FOXE1, PDE8B, CAPZB and PDE10A with thyroid traits: a Genetics of Diabetes Audit and Research Tayside study (GoDARTS). | 5 |
| 28803871 | 2017 | An RNAi Screen in a Novel Model of Oriented Divisions Identifies the Actin-Capping Protein Z β as an Essential Regulator of Spindle Orientation. | 11 |
| 28104696 | 2017 | Systematic characterization of human testis-specific actin capping protein β3 as a possible biomarker for male infertility. | 6 |
| 28727628 | 2017 | Replication confirms the association of loci in FOXE1, PDE8B, CAPZB and PDE10A with thyroid traits: a Genetics of Diabetes Audit and Research Tayside study (GoDARTS). | 5 |
| 28803871 | 2017 | An RNAi Screen in a Novel Model of Oriented Divisions Identifies the Actin-Capping Protein Z β as an Essential Regulator of Spindle Orientation. | 11 |
| 26758871 | 2016 | Actin capping protein CAPZB regulates cell morphology, differentiation, and neural crest migration in craniofacial morphogenesis†. | 21 |
| 26965049 | 2016 | Expression of F-actin-capping protein subunit beta, CAPZB, is associated with cell growth and motility in epithelioid sarcoma. | 10 |
| 26758871 | 2016 | Actin capping protein CAPZB regulates cell morphology, differentiation, and neural crest migration in craniofacial morphogenesis†. | 21 |
Citation
Dessen P
CAPZB (capping actin protein of muscle Z-line subunit beta)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/911/capzb-(capping-actin-protein-of-muscle-z-line-subunit-beta)
