CCL15 (C-C motif chemokine ligand 15)

2003-05-01  

Identity

HGNC
CCL15
LOCATION
17q12
LOCUSID
6359
ALIAS
HCC-2,HMRP-2B,LKN-1,LKN1,MIP-1

Other Information

Locus ID:

NCBI: 6359
MIM: 601393
HGNC: 10613
Ensembl: ENSG00000275718

Variants:

dbSNP: 6359
ClinVar: 6359
TCGA: ENSG00000275718
COSMIC: CCL15

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000275718ENST00000614368A0A087X1J9
ENSG00000275718ENST00000617897Q16663

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Cytokine-cytokine receptor interactionKEGGko04060
Cytokine-cytokine receptor interactionKEGGhsa04060
Chemokine signaling pathwayKEGGko04062
Chemokine signaling pathwayKEGGhsa04062

References

Pubmed IDYearTitleCitations
177034122007Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes.100
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
222795512012Evaluation of a previously suggested plasma biomarker panel to identify Alzheimer's disease.40
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
192589232009Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes.26
263419192016Loss of SMAD4 Promotes Colorectal Cancer Progression by Accumulation of Myeloid-Derived Suppressor Cells through the CCL15-CCR1 Chemokine Axis.24
152514372004Angiogenic activity of human CC chemokine CCL15 in vitro and in vivo.19
198125442010A novel role for constitutively expressed epithelial-derived chemokines as antibacterial peptides in the intestinal mucosa.19
205032872010Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls.17
274929742017Loss of SMAD4 Promotes Lung Metastasis of Colorectal Cancer by Accumulation of CCR1+ Tumor-Associated Neutrophils through CCL15-CCR1 Axis.17

Citation

Dessen P

CCL15 (C-C motif chemokine ligand 15)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/941/ccl15-(c-c-motif-chemokine-ligand-15)