Identity
HGNC
LOCATION
9p13.3
LOCUSID
ALIAS
6Ckine,CKb9,ECL,SCYA21,SLC,TCA4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6366
MIM: 602737
HGNC: 10620
Ensembl: ENSG00000137077
Variants:
dbSNP: 6366
ClinVar: 6366
TCGA: ENSG00000137077
COSMIC: CCL21
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000137077 | ENST00000259607 | O00585 |
| ENSG00000137077 | ENST00000378792 | Q5VZ73 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38553809 | 2024 | CCL21 and CLDN11 Are Key Driving Factors of Lymph Node Metastasis in Gastric Cancer. | 0 |
| 38553809 | 2024 | CCL21 and CLDN11 Are Key Driving Factors of Lymph Node Metastasis in Gastric Cancer. | 0 |
| 36652748 | 2023 | Plasma levels of CCL21, but not CCL19, independently predict future coronary events in a prospective population-based cohort. | 1 |
| 36675182 | 2023 | Heparin Specifically Interacts with Basic BBXB Motifs of the Chemokine CCL21 to Define CCR7 Signaling. | 2 |
| 36723865 | 2023 | CCL19 (rs3136658) and CCL21 (rs2812377) Variants Are Associated With Susceptibility and Related Mortality of SARS-CoV-2 Infection. | 1 |
| 37314567 | 2023 | CCL21-CCR7 signaling promotes microglia/macrophage recruitment and chemotherapy resistance in glioblastoma. | 1 |
| 37377898 | 2023 | Chemokine Analysis in Patients with Metastatic Uveal Melanoma Suggests a Role for CCL21 Signaling in Combined Epigenetic Therapy and Checkpoint Immunotherapy. | 0 |
| 36652748 | 2023 | Plasma levels of CCL21, but not CCL19, independently predict future coronary events in a prospective population-based cohort. | 1 |
| 36675182 | 2023 | Heparin Specifically Interacts with Basic BBXB Motifs of the Chemokine CCL21 to Define CCR7 Signaling. | 2 |
| 36723865 | 2023 | CCL19 (rs3136658) and CCL21 (rs2812377) Variants Are Associated With Susceptibility and Related Mortality of SARS-CoV-2 Infection. | 1 |
| 37314567 | 2023 | CCL21-CCR7 signaling promotes microglia/macrophage recruitment and chemotherapy resistance in glioblastoma. | 1 |
| 37377898 | 2023 | Chemokine Analysis in Patients with Metastatic Uveal Melanoma Suggests a Role for CCL21 Signaling in Combined Epigenetic Therapy and Checkpoint Immunotherapy. | 0 |
| 35380893 | 2022 | CCL21 and IP10 as serum biomarkers for pulmonary involvement in systemic lupus erythematosus. | 0 |
| 35690148 | 2022 | Plasminogen and plasmin can bind to human T cells and generate truncated CCL21 that increases dendritic cell chemotactic responses. | 5 |
| 36211384 | 2022 | Target organ expression and biomarker characterization of chemokine CCL21 in systemic sclerosis associated pulmonary arterial hypertension. | 5 |
Citation
Dessen P
CCL21 (C-C motif chemokine ligand 21)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/943/ccl21-(c-c-motif-chemokine-ligand-21)
