CCL7 (C-C motif chemokine ligand 7)

2003-06-01  

Identity

HGNC
CCL7
LOCATION
17q12
LOCUSID
6354
ALIAS
FIC,MARC,MCP-3,MCP3,NC28,SCYA6,SCYA7

Other Information

Locus ID:

NCBI: 6354
MIM: 158106
HGNC: 10634
Ensembl: ENSG00000108688

Variants:

dbSNP: 6354
ClinVar: 6354
TCGA: ENSG00000108688
COSMIC: CCL7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000108688ENST00000378569P80098
ENSG00000108688ENST00000394627A8MVH1
ENSG00000108688ENST00000394630A8MX17

Expression (GTEx)

0
1
2
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Cytokine-cytokine receptor interactionKEGGko04060
Cytokine-cytokine receptor interactionKEGGhsa04060
Chemokine signaling pathwayKEGGko04062
Chemokine signaling pathwayKEGGhsa04062
IL-17 signaling pathwayKEGGko04657
IL-17 signaling pathwayKEGGhsa04657

References

Pubmed IDYearTitleCitations
383169632024Nucleus pulposus cells regulate macrophages in degenerated intervertebral discs via the integrated stress response-mediated CCL2/7-CCR2 signaling pathway.0
389148032024TREM1(+) tumor-associated macrophages secrete CCL7 to promote hepatocellular carcinoma metastasis.0
383169632024Nucleus pulposus cells regulate macrophages in degenerated intervertebral discs via the integrated stress response-mediated CCL2/7-CCR2 signaling pathway.0
389148032024TREM1(+) tumor-associated macrophages secrete CCL7 to promote hepatocellular carcinoma metastasis.0
365852042023Serum CCL7 Is a Novel Prognostic Biomarker of Metastatic Colorectal Cancer.4
365852042023Serum CCL7 Is a Novel Prognostic Biomarker of Metastatic Colorectal Cancer.4
357158472022CCL7 playing a dominant role in recruiting early OCPs to facilitate osteolysis at metastatic site of colorectal cancer.0
361184152022LINC01094/SPI1/CCL7 Axis Promotes Macrophage Accumulation in Lung Adenocarcinoma and Tumor Cell Dissemination.10
362744852022The role of CCL2, CCL7, ICAM-1, and VCAM-1 in interaction of endothelial cells and natural killer cells.7
357158472022CCL7 playing a dominant role in recruiting early OCPs to facilitate osteolysis at metastatic site of colorectal cancer.0
361184152022LINC01094/SPI1/CCL7 Axis Promotes Macrophage Accumulation in Lung Adenocarcinoma and Tumor Cell Dissemination.10
362744852022The role of CCL2, CCL7, ICAM-1, and VCAM-1 in interaction of endothelial cells and natural killer cells.7
338764132021The increased intrathecal expression of the monocyte-attracting chemokines CCL7 and CXCL12 in tick-borne encephalitis.7
338764132021The increased intrathecal expression of the monocyte-attracting chemokines CCL7 and CXCL12 in tick-borne encephalitis.7
320608442020CCL7 Signaling in the Tumor Microenvironment.18

Citation

Dessen P

CCL7 (C-C motif chemokine ligand 7)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/946/ccl7-(c-c-motif-chemokine-ligand-7)