Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 892
MIM: 123838
HGNC: 1581
Ensembl: ENSG00000112237
Variants:
dbSNP: 892
ClinVar: 892
TCGA: ENSG00000112237
COSMIC: CCNC
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34197614 | 2021 | Genome-wide CRISPR screens reveal cyclin C as synthetic survival target of BRCA2. | 9 |
| 34329458 | 2021 | Loss of Cyclin C or CDK8 provides ATR inhibitor resistance by suppressing transcription-associated replication stress. | 17 |
| 34197614 | 2021 | Genome-wide CRISPR screens reveal cyclin C as synthetic survival target of BRCA2. | 9 |
| 34329458 | 2021 | Loss of Cyclin C or CDK8 provides ATR inhibitor resistance by suppressing transcription-associated replication stress. | 17 |
| 30516433 | 2019 | Cyclin C directly stimulates Drp1 GTP affinity to mediate stress-induced mitochondrial hyperfission. | 22 |
| 30516433 | 2019 | Cyclin C directly stimulates Drp1 GTP affinity to mediate stress-induced mitochondrial hyperfission. | 22 |
| 29440396 | 2018 | Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19. | 32 |
| 29440396 | 2018 | Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19. | 32 |
| 25986860 | 2015 | Cyclin C interacts with steroid receptor coactivator 2 and upregulates cell cycle genes in MCF-7 cells. | 2 |
| 26042770 | 2015 | mTORC1 Down-Regulates Cyclin-Dependent Kinase 8 (CDK8) and Cyclin C (CycC). | 17 |
| 25986860 | 2015 | Cyclin C interacts with steroid receptor coactivator 2 and upregulates cell cycle genes in MCF-7 cells. | 2 |
| 26042770 | 2015 | mTORC1 Down-Regulates Cyclin-Dependent Kinase 8 (CDK8) and Cyclin C (CycC). | 17 |
| 24754906 | 2014 | All-atomic molecular dynamic studies of human CDK8: insight into the A-loop, point mutations and binding with its partner CycC. | 12 |
| 25344755 | 2014 | Cyclin C is a haploinsufficient tumour suppressor. | 69 |
| 24754906 | 2014 | All-atomic molecular dynamic studies of human CDK8: insight into the A-loop, point mutations and binding with its partner CycC. | 12 |
Citation
Dessen P
CCNC (cyclin C)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/954/ccnc-(cyclin-c)
