CD1D (CD1d molecule)

2003-11-01  

Identity

HGNC
LOCATION
1q23.1
LOCUSID
ALIAS
CD1A,R3,R3G1

Other Information

Locus ID:

NCBI: 912
MIM: 188410
HGNC: 1637
Ensembl: ENSG00000158473
IMGT/GENE-DB:

Variants:

dbSNP: 912
ClinVar: 912
TCGA: ENSG00000158473
COSMIC: CD1D

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000158473ENST00000368171P15813

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Pathways

PathwaySourceExternal ID
Tight junctionKEGGko04530
Hematopoietic cell lineageKEGGko04640
Tight junctionKEGGhsa04530
Hematopoietic cell lineageKEGGhsa04640
AmoebiasisKEGGko05146
AmoebiasisKEGGhsa05146
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellREACTOMER-HSA-198933

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
377355002024Cancer-associated fibroblasts express CD1d and activate invariant natural killer T cells under cellular stress.0
377355002024Cancer-associated fibroblasts express CD1d and activate invariant natural killer T cells under cellular stress.0
370779202023Epigenetic control of CD1D expression as a mechanism of resistance to immune checkpoint therapy in poorly immunogenic melanomas.3
370779202023Epigenetic control of CD1D expression as a mechanism of resistance to immune checkpoint therapy in poorly immunogenic melanomas.3
331285832021CD1d expression in glioblastoma is a promising target for NKT cell-based cancer immunotherapy.12
331285832021CD1d expression in glioblastoma is a promising target for NKT cell-based cancer immunotherapy.12
310503672020Expression of CD1d by astrocytes corresponds with relative activity in multiple sclerosis lesions.2
322447592020Structural Dynamics of the Lipid Antigen-Binding Site of CD1d Protein.4
325125112020Low oxygen saturation during sleep reduces CD1D and RAB20 expressions that are reversed by CPAP therapy.6
310503672020Expression of CD1d by astrocytes corresponds with relative activity in multiple sclerosis lesions.2
322447592020Structural Dynamics of the Lipid Antigen-Binding Site of CD1d Protein.4
325125112020Low oxygen saturation during sleep reduces CD1D and RAB20 expressions that are reversed by CPAP therapy.6
308647132019CD1d highly expressed on DCs reduces lung tumor burden by enhancing antitumor immunity.7
313547102019Invariant NKT Cells From Donor Lymphocyte Infusions (DLI-iNKTs) Promote ex vivo Lysis of Leukemic Blasts in a CD1d-Dependent Manner.10
315608332019Increased cytoplasmatic expression of cancer immune surveillance receptor CD1d in anaplastic thyroid carcinomas.5

Citation

Dessen P

CD1D (CD1d molecule)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/970/cd1d-(cd1d-molecule)