Identity
HGNC
LOCATION
19q13.41
LOCUSID
ALIAS
SIGLEC-3,SIGLEC3,p67
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 945
MIM: 159590
HGNC: 1659
Ensembl: ENSG00000105383
Variants:
dbSNP: 945
ClinVar: 945
TCGA: ENSG00000105383
COSMIC: CD33
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164749431 | gemtuzumab ozogamicin | Chemical | ClinicalAnnotation, VariantAnnotation | associated | PD | ||
| PA166123207 | overall survival | Disease | VariantAnnotation | associated | PD | ||
| PA444760 | Leukemia, Myeloid, Acute | Disease | ClinicalAnnotation, VariantAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35940942 | 2023 | CD33 isoforms in microglia and Alzheimer's disease: Friend and foe. | 10 |
| 36831269 | 2023 | Alzheimer's Disease-Associated Alternative Splicing of CD33 Is Regulated by the HNRNPA Family Proteins. | 0 |
| 37081561 | 2023 | CD33 as a leukocyte-associated marker expressed on human spermatozoa. | 1 |
| 37479176 | 2023 | CD33 polymorphisms and Parkinson's disease Parkinson's disease in northern Chinese Han population: A case-control study. | 0 |
| 37506557 | 2023 | Plasma proteomic profiling identifies CD33 as a marker of HIV control in natural infection and after therapeutic vaccination. | 1 |
| 37519183 | 2023 | Lack of Association between CD33 rs3865444 and Amyotrophic Lateral Sclerosis: A Case-Control Study. | 0 |
| 35940942 | 2023 | CD33 isoforms in microglia and Alzheimer's disease: Friend and foe. | 10 |
| 36831269 | 2023 | Alzheimer's Disease-Associated Alternative Splicing of CD33 Is Regulated by the HNRNPA Family Proteins. | 0 |
| 37081561 | 2023 | CD33 as a leukocyte-associated marker expressed on human spermatozoa. | 1 |
| 37479176 | 2023 | CD33 polymorphisms and Parkinson's disease Parkinson's disease in northern Chinese Han population: A case-control study. | 0 |
| 37506557 | 2023 | Plasma proteomic profiling identifies CD33 as a marker of HIV control in natural infection and after therapeutic vaccination. | 1 |
| 37519183 | 2023 | Lack of Association between CD33 rs3865444 and Amyotrophic Lateral Sclerosis: A Case-Control Study. | 0 |
| 35123618 | 2022 | [The Relationship between the Expressions of CD33 and CD13 and the Prognosis of Patients with Multiple Myeloma]. | 0 |
| 35408990 | 2022 | CD33 rs2455069 SNP: Correlation with Alzheimer's Disease and Hypothesis of Functional Role. | 7 |
| 36051360 | 2022 | No Evidence that CD33 rs12459419 Polymorphism Predicts Gemtuzumab Ozogamicin Response in Consolidation Treatment of Acute Myeloid Leukemia Patients: Experience of the PETHEMA Group. | 0 |
Citation
Dessen P
CD33 (CD33 molecule)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/974/cd33-(cd33-molecule)
