CD63 (CD63 molecule)

2003-06-01  

Identity

HGNC
CD63
LOCATION
12q13.2
LOCUSID
967
ALIAS
LAMP-3,ME491,MLA1,OMA81H,TSPAN30
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 967
MIM: 155740
HGNC: 1692
Ensembl: ENSG00000135404

Variants:

dbSNP: 967
ClinVar: 967
TCGA: ENSG00000135404
COSMIC: CD63

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000135404ENST00000257857P08962
ENSG00000135404ENST00000257857A0A024RB05
ENSG00000135404ENST00000420846P08962
ENSG00000135404ENST00000420846A0A024RB05
ENSG00000135404ENST00000546457F8VNT9
ENSG00000135404ENST00000546939P08962
ENSG00000135404ENST00000548160F8VV56
ENSG00000135404ENST00000548898F8VV56
ENSG00000135404ENST00000549117P08962
ENSG00000135404ENST00000549117A0A024RB05
ENSG00000135404ENST00000550050F8VX62
ENSG00000135404ENST00000550776P08962
ENSG00000135404ENST00000551173F8W022
ENSG00000135404ENST00000552067F8VV56
ENSG00000135404ENST00000552164F8VWK8
ENSG00000135404ENST00000552692P08962
ENSG00000135404ENST00000552692A0A024RB05
ENSG00000135404ENST00000552754P08962

Expression (GTEx)

0
500
1000
1500
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
LysosomeKEGGko04142
LysosomeKEGGhsa04142
Proteoglycans in cancerKEGGhsa05205
Proteoglycans in cancerKEGGko05205
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
HemostasisREACTOMER-HSA-109582
Platelet activation, signaling and aggregationREACTOMER-HSA-76002
Response to elevated platelet cytosolic Ca2+REACTOMER-HSA-76005
Platelet degranulationREACTOMER-HSA-114608
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
383307302024The subtilisin-like protease furin regulates hemin-induced CD63 surface expression on platelets.0
386826962024Arf GTPase-Activating proteins ADAP1 and ARAP1 regulate incorporation of CD63 in multivesicular bodies.0
383307302024The subtilisin-like protease furin regulates hemin-induced CD63 surface expression on platelets.0
386826962024Arf GTPase-Activating proteins ADAP1 and ARAP1 regulate incorporation of CD63 in multivesicular bodies.0
371984272023Lack of involvement of CD63 and CD9 tetraspanins in the extracellular vesicle content delivery process.9
375253982023Differential proteomics argues against a general role for CD9, CD81 or CD63 in the sorting of proteins into extracellular vesicles.5
371984272023Lack of involvement of CD63 and CD9 tetraspanins in the extracellular vesicle content delivery process.9
375253982023Differential proteomics argues against a general role for CD9, CD81 or CD63 in the sorting of proteins into extracellular vesicles.5
350464802022A potential target gene CD63 for different degrees of intervertebral disc degeneration.1
353509782022CD63-positive extracellular vesicles are potential diagnostic biomarkers of pancreatic ductal adenocarcinoma.8
357874462022Aberrant TIMP-1 overexpression in tumor-associated fibroblasts drives tumor progression through CD63 in lung adenocarcinoma.10
363501532022LAMP3/CD63 Expression in Early and Late Endosomes in Human Vaginal Epithelial Cells Is Associated with Enhancement of HSV-2 Infection.1
350464802022A potential target gene CD63 for different degrees of intervertebral disc degeneration.1
353509782022CD63-positive extracellular vesicles are potential diagnostic biomarkers of pancreatic ductal adenocarcinoma.8
357874462022Aberrant TIMP-1 overexpression in tumor-associated fibroblasts drives tumor progression through CD63 in lung adenocarcinoma.10

Citation

Dessen P

CD63 (CD63 molecule)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/986/cd63-(cd63-molecule)