Identity
HGNC
LOCATION
12p13.31
LOCUSID
ALIAS
AIM,BL-AC/P26,CLEC2C,EA1,GP32/28,MLR-3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 969
MIM: 107273
HGNC: 1694
Ensembl: ENSG00000110848
Variants:
dbSNP: 969
ClinVar: 969
TCGA: ENSG00000110848
COSMIC: CD69
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000110848 | ENST00000228434 | Q07108 |
| ENSG00000110848 | ENST00000228434 | Q53ZX0 |
| ENSG00000110848 | ENST00000536709 | B4E009 |
Expression (GTEx)
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA165292659 | tocilizumab | Chemical | ClinicalAnnotation | associated | PD | 27339827 | |
| PA443434 | Arthritis, Rheumatoid | Disease | ClinicalAnnotation | associated | PD | 27339827 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36854451 | 2023 | Cancer cell-derived CD69 induced under lipid and oxygen starvation promotes ovarian cancer progression through fibronectin. | 3 |
| 37156819 | 2023 | CD69 serves as a potential diagnostic and prognostic biomarker for hepatocellular carcinoma. | 0 |
| 37715025 | 2023 | The heterogeneity of tumour immune microenvironment revealing the CRABP2/CD69 signature discriminates distinct clinical outcomes in breast cancer. | 3 |
| 36854451 | 2023 | Cancer cell-derived CD69 induced under lipid and oxygen starvation promotes ovarian cancer progression through fibronectin. | 3 |
| 37156819 | 2023 | CD69 serves as a potential diagnostic and prognostic biomarker for hepatocellular carcinoma. | 0 |
| 37715025 | 2023 | The heterogeneity of tumour immune microenvironment revealing the CRABP2/CD69 signature discriminates distinct clinical outcomes in breast cancer. | 3 |
| 35690994 | 2022 | Combined assessment of S- and N-specific IL-2 and IL-13 secretion and CD69 neo-expression for discrimination of post-infection and post-vaccination cellular SARS-CoV-2-specific immune response. | 5 |
| 36518755 | 2022 | Machine learning links different gene patterns of viral infection to immunosuppression and immune-related biomarkers in severe burns. | 0 |
| 35690994 | 2022 | Combined assessment of S- and N-specific IL-2 and IL-13 secretion and CD69 neo-expression for discrimination of post-infection and post-vaccination cellular SARS-CoV-2-specific immune response. | 5 |
| 36518755 | 2022 | Machine learning links different gene patterns of viral infection to immunosuppression and immune-related biomarkers in severe burns. | 0 |
| 32408340 | 2021 | Apoptosis inhibitor of macrophage as a biomarker for disease activity in Japanese children with IgA nephropathy and Henoch-Schönlein purpura nephritis. | 6 |
| 33627405 | 2021 | T cells selectively filter oscillatory signals on the minutes timescale. | 22 |
| 34344244 | 2021 | Prognostic Relevance of Concordant Expression CD69 and CD56 in Response to Bortezomib Combination Therapy in Multiple Myeloma Patients. | 6 |
| 34427648 | 2021 | CD4+ T cells in inflammatory diseases: pathogenic T-helper cells and the CD69-Myl9 system. | 4 |
| 32408340 | 2021 | Apoptosis inhibitor of macrophage as a biomarker for disease activity in Japanese children with IgA nephropathy and Henoch-Schönlein purpura nephritis. | 6 |
Citation
Dessen P
CD69 (CD69 molecule)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/988/cd69-(cd69-molecule)
