t(5;15)(p15;q11)

1999-03-01   Nyla A. Heerema, PhD 

1.The Ohio State University, Division of Clinical Pathology, Department of Pathology, 167 Hamilton Hall, 1645 Neil Ave, Columbus, OH 43210, USA

Clinics and Pathology

Disease

B-cell, precursor ALL

Phenotype stem cell origin

L1, CD10+/-, CD24+

Epidemiology

5 reported cases; Infant ALL, age 1.5-7 months at diagnosis

Prognosis

CR in all cases; 1 CNS relapse

Cytogenetics

Cytogenetics morphological

t(5;15)(p15;q11-13)

Cytogenetics molecular

not done

Additional anomalies

+14; +22 one case each

Variants

none reported

Genes Involved and Proteins

Article Bibliography

Pubmed IDLast YearTitleAuthors
81617941994Cytogenetic features of infants less than 12 months of age at diagnosis of acute lymphoblastic leukemia: impact of the 11q23 breakpoint on outcome: a report of the Childrens Cancer Group.Heerema NA et al

Citation

Nyla A. Heerema, PhD

t(5;15)(p15;q11)

Atlas Genet Cytogenet Oncol Haematol. 1999-03-01

Online version: http://atlasgeneticsoncology.org/haematological/1149/t(5