t(5;16)(q33;q22)
2008-03-01 Jean-Loup Huret Affiliation1.Genetics, Dept Medical Information, University of Poitiers, CHU Poitiers Hospital, F-86021 Poitiers, France
Clinics and Pathology
Disease
Acute myeloid leukemia (AML)
Epidemiology
Only two cases to date, a 10-month-old male infant with M4-AML, who entered remission, and a 60-year-old male patient with M1-AML who died 4 months after diagnosis. Both patients presented with marked eosinophilia (Bhambhani et al., 1986; Sanada et al., 1989).
Genes Involved and Proteins
Note
Genes involved in this structural anomaly are unknown, although it is likely that CBFb is involved in the disease.
Article Bibliography
| Pubmed ID | Last Year | Title | Authors |
|---|---|---|---|
| 3455859 | 1986 | Acute myelomonocytic leukemia type M4 with bone marrow eosinophilia and t(5;16)(q33;q22). | Bhambhani K et al |
| 2790769 | 1989 | Acute myelogenous leukemia (FAB M1) associated with t(5;16) and eosinophilia. Report of an additional case. | Sanada I et al |
Citation
Jean-Loup Huret
t(5;16)(q33;q22)
Atlas Genet Cytogenet Oncol Haematol. 2008-03-01
Online version: http://atlasgeneticsoncology.org/haematological/1151/t(5
