t(3;8)(q21;q24) in myeloid malignancies

2008-06-01   Jean-Loup Huret 

1.Genetics, Dept Medical Information, University of Poitiers, CHU Poitiers Hospital, F-86021 Poitiers, France

Clinics and Pathology

Disease

Acute myeloid leukemia (AML)

Epidemiology

Three patients to date, a 9-year-old girl with M4-AML, a 48-year-old male patient with M5-AML, and a 74-year-old female patient with therapy related AML(t-AML), M1 subtype, having occurred after treatment of a breast cancer (Haltrich et al., 2006; Charrin et al., 2002; Lindvall et al., 2001).

Prognosis

No individual data.

Note

Genes involved in this translocation are unknown.

Bibliography

Pubmed IDLast YearTitleAuthors
119603922002Structural rearrangements of chromosome 3 in 57 patients with acute myeloid leukemia: clinical, hematological and cytogenetic features.Charrin C et al
164054332006Multipoint interphase FISH analysis of chromosome 3 abnormalities in 28 childhood AML patients.Haltrich I et al
116944012001Molecular cytogenetic characterization of acute myeloid leukemia and myelodysplastic syndromes with multiple chromosome rearrangements.Lindvall C et al

Citation

Jean-Loup Huret

t(3;8)(q21;q24) in myeloid malignancies

Atlas Genet Cytogenet Oncol Haematol. 2008-06-01

Online version: http://atlasgeneticsoncology.org/haematological/1249/t(3;8)(q21;q24)-in-myeloid-malignancies