t(2;12)(q31;p13) ETV6/?

2006-11-01   Jean-Loup Huret 

1.Genetics, Dept Medical Information, University of Poitiers; CHU Poitiers Hospital, F-86021 Poitiers, France

Clinics and Pathology

Disease

Non Hodgkin lymphoma (NHL) and myelodysplastic syndrome (chronic myelomonocytic leukemia (CMML)

Epidemiology

Only 2 cases to date (male patients): 1 NHL aged 30 yrs and 1 CMML aged 78 yrs

Prognosis

The CMML case died 2 yrs 9 mths after diagnosis

Genes Involved and Proteins

Note
ETV6 was found involved in the NHL case

Bibliography

Pubmed IDLast YearTitleAuthors
93897051997Heterogeneity in the breakpoints in balanced rearrangements involving band 12p13 in hematologic malignancies identified by fluorescence in situ hybridization: TEL (ETV6 ) is involved in only one half.Sato Y et al

Summary

Atlas Image
t(2;12)(q31;p13) G- banding - Courtesy Melanie Zenger and Claudia Haferlach.

Citation

Jean-Loup Huret

t(2;12)(q31;p13) ETV6/?

Atlas Genet Cytogenet Oncol Haematol. 2006-11-01

Online version: http://atlasgeneticsoncology.org/haematological/1459/t(2;12)(q31;p13)

External Links