1.Kuwait Cancer Control Center, Kuwait email@example.com
Unbalanced chromosome translocations involving all or part of the whole long arm of chromosome 1 and the short arms of acrocentric chromosomes are widely reported in human neoplasia. Among them, chromosome translocations between the long arm of chromosome 1 and chromosome 21 have been reported in patients with various conditions, including myeloid malignancies, acute lymphoblastic leukemia, multiple myeloma and lymphomas.
der(21)t(1;21)(q11-12;p11-13) and der(21)t(1;21)(q21-32;p11-13)
Atlas Genet Cytogenet Oncol Haematol. 2017-10-01
Online version: http://atlasgeneticsoncology.org/haematological/1478/der(21)t(1;21)(q11-12;p11-13))