2009-05-01   Jean-Loup Huret 

1.Genetics, Dept Medical Information, University of Poitiers, CHU Poitiers Hospital, F-86021 Poitiers, France

Clinics and Pathology


Non Hodgkin lymphoma and acute lymphoblastic lymphoma.

Phenotype stem cell origin

B-cell malignancies.


3 cases to date: a stage IIIA mantle cell lymphoma in a male aged 58 years (Au et al., 2000; Au et al., 2002), a follicular lymphoma in a female patient aged 44 years (Chen et al., 2001), and a pre-B acute lymphoblastic leukemia (ALL) in a female patient aged 60 years (Pedersen et al., 2001).


Clinical data is available in the mantle cell lymphoma case, who reached complete remission, relapsed 2 years later, and died.

Genes Involved and Proteins

In the follicular lymphoma case with t(1;14)(q21;q32), there was deregulation of FCGR2B expression due to FCGR2B/IgH juxtaposition


Pubmed IDLast YearTitleAuthors
121531652002Cytogenetic analysis in mantle cell lymphoma: a review of 214 cases.Au WY et al
1106448020008q24 translocations in blastic transformation of mantle cell lymphoma.Au WY et al
117536462001Deregulation of FCGR2B expression by 1q21 rearrangements in follicular lymphomas.Chen W et al
114544222001Cytogenetic aberrations in adult acute lymphocytic leukemia: optimal technique may influence the results.Pedersen RK et al


Jean-Loup Huret


Atlas Genet Cytogenet Oncol Haematol. 2009-05-01

Online version: http://atlasgeneticsoncology.org/haematological/1550/t(8;9)(q24;q13)