1.Kuwait Cancer Control Center, Department of Hematology, Laboratory of Cancer Genetics, Kuwait; annaadria@yahoo.com
Isochromosomes are nonrandom chromosomal anomalies in acute lymphoblastic leukemia (ALL), but relatively few patients ALL and i(8)(q10) have been reported. In the majority of cases, i(8)(q10) was part of complex karyotypes, suggesting that it is a secondary chromosomal abnormality in ALL associated with clonal evolution.
Adriana Zamecnikova
i(8)(q10) in ALL
Atlas Genet Cytogenet Oncol Haematol. 2017-06-01
Online version: http://atlasgeneticsoncology.org/haematological/2052/i(8)(q10)-in-all