FLT3/FLT3 (13q12)

2018-01-01   Philippe Dessen  , Jean-Loup Huret  

Clinics and Pathology

Disease

Acute megakaryoblastic leukemia (FAB type M7)

Genes Involved and Proteins

Gene name
Location
13q12.2
Gene name
Location
13q12.2

Highly cited references

Pubmed IDYearTitleCitations
246393462014Cutting edge: Flt3 ligand mediates STAT3-independent expansion but STAT3-dependent activation of myeloid-derived suppressor cells.25
340977792021Dendritic cell Flt3 - regulation, roles and repercussions for immunotherapy.0
286016362017The angiogenic factor Egfl7 alters thymogenesis by activating Flt3 signaling.0
317187642019FLT3 and FLT3-ITD gene mutations and prognosis in patients with acute myeloid leukemia.0
315452192019FLT3/FLT3L-mediated CD103(+) dendritic cells alleviates hepatic ischemia-reperfusion injury in mice via activation of treg cells.0
165797562006Evaluation of dysregulation of the receptor tyrosine kinases Kit, Flt3, and Met in histiocytic sarcomas of dogs.0

Article Bibliography

Pubmed IDLast YearTitleAuthors
281127372017Pediatric non-Down syndrome acute megakaryoblastic leukemia is characterized by distinct genomic subsets with varying outcomes.de Rooij JD et al

Summary

Fusion gene

FLT3/FLT3 FLT3 (13q12.2) FLT3 (13q12.2)

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to  How to contribute

Citation

Philippe Dessen ; Jean-Loup Huret

FLT3/FLT3 (13q12)

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/2731/flt3-flt3-(13q12)