Clinics and Pathology
Disease
Acute megakaryoblastic leukemia (FAB type M7)
Highly cited references
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 28174417 | 2017 | AMKL chimeric transcription factors are potent inducers of leukemia. | 45 |
| 26690545 | 2015 | MN1-Fli1 oncofusion transforms murine hematopoietic progenitor cells into acute megakaryoblastic leukemia cells. | 14 |
Article Bibliography
| Pubmed ID | Last Year | Title | Authors |
|---|---|---|---|
| 23153540 | 2012 | An Inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia. | Gruber TA et al |
| 28112737 | 2017 | Pediatric non-Down syndrome acute megakaryoblastic leukemia is characterized by distinct genomic subsets with varying outcomes. | de Rooij JD et al |
Summary
Fusion gene
MN1/FLI1 MN1 (22q12.1) FLI1 (11q24.3)
Note
Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to How to contribute
if you are an author who wish to write a full paper/card on this translocation,go to How to contribute
Citation
Jean-Loup Huret ; Philippe Dessen
t(11;22)(q24;q12) MN1/FLI1
Atlas Genet Cytogenet Oncol Haematol. 2018-01-01
Online version: http://atlasgeneticsoncology.org/haematological/2972
