t(6;7)(q23;q36) MYB/MNX1

2018-01-01   Jean-Loup Huret  , Philippe Dessen  

Clinics and Pathology

Disease

Acute myelomonocytic leukemia (FAB type M4)

Genes Involved and Proteins

Gene name
MYB
Location
6q23.3
Gene name
MNX1
Location
7q36.3

Bibliography

Pubmed IDLast YearTitleAuthors
155402222005Activation of HLXB9 by juxtaposition with MYB via formation of t(6;7)(q23;q36) in an AML-M4 cell line (GDM-1).Nagel S et al

Summary

Fusion gene

MYB/MNX1 MYB (6q23.3) MNX1 (7q36.3)

Note

Non-annotated chromosomal abnormality. Preliminary data :
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Citation

Jean-Loup Huret ; Philippe Dessen

t(6;7)(q23;q36) MYB/MNX1

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/2984/t(6;7)(q23;q36)