(Note: the fusion was discovered by NGS. Many chromosome rearrangement mechanisms such as translocation, inversion,deletion or complex rearrangement may lead to the same fusion)
Note
Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to u00a0How to contribute
Summary
Note
Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to How to contribute
if you are an author who wish to write a full paper/card on this translocation,go to How to contribute
Highly cited references
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38882060 | 2024 | Molecular and therapeutic advancements in Capicua (CIC)-rearranged sarcoma. | 86 |
| 26735859 | 2016 | Recurrent CIC Gene Abnormalities in Angiosarcomas: A Molecular Study of 120 Cases With Concurrent Investigation of PLCG1, KDR, MYC, and FLT4 Gene Alterations. | 46 |
| 31595628 | 2020 | Targeted fusion analysis can aid in the classification and treatment of pediatric glioma, ependymoma, and glioneuronal tumors. | 43 |
| 36964296 | 2023 | Pediatric-type high-grade neuroepithelial tumors with CIC gene fusion share a common DNA methylation signature. | 31 |
| 35859319 | 2022 | A case of CIC-rearranged sarcoma with CIC-LEUTX gene fusion in spinal cord. | 27 |
| 38036973 | 2023 | Renal CIC-LEUTX rearranged sarcoma with multiple pulmonary metastases: a case report and literature review. | 26 |
| 39525005 | 2024 | Capicua transcriptional repressor (CIC)-rearranged sarcoma harboring CIC-LEUTX fusion with renal involvement: a rare case report. | 23 |
| 38926750 | 2024 | Pediatric central nervous system tumor with CIC::LEUTX fusion: a diagnostic challenge. | 20 |
| 33344249 | 2020 | Case Report: A Unique Case of Pediatric Central Nervous System Embryonal Tumor Harboring the CIC-LEUTX Fusion, Germline NBN Variant and Somatic TSC2 Mutation: Expanding the Spectrum of CIC-Rearranged Neoplasia. | 20 |
| 39985394 | 2025 | Comparison of Molecular Testing Methodologies for CIC-Rearranged Sarcomas. | 0 |
Article Bibliography
| Pubmed ID | Last Year | Title | Authors |
|---|---|---|---|
| 26735859 | 2016 | Recurrent CIC Gene Abnormalities in Angiosarcomas: A Molecular Study of 120 Cases With Concurrent Investigation of PLCG1, KDR, MYC, and FLT4 Gene Alterations. | Huang SC et al |
Citation
Jean-Loup Huret ; Philippe Dessen
CIC/LEUTX (19q13)
Atlas Genet Cytogenet Oncol Haematol. 0000-00-00
Online version: http://atlasgeneticsoncology.org/solid-tumor/103324/cic-leutx-(19q13)
