(Note: the fusion was discovered by NGS. Many chromosome rearrangement mechanisms such as translocation, inversion,deletion or complex rearrangement may lead to the same fusion)
Note
Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to u00a0How to contribute
Summary
Note
Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to How to contribute
if you are an author who wish to write a full paper/card on this translocation,go to How to contribute
Highly cited references
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 9121481 | 1997 | Role of the nucleophosmin (NPM) portion of the non-Hodgkin's lymphoma-associated NPM-anaplastic lymphoma kinase fusion protein in oncogenesis. | 63 |
| 25602801 | 2015 | Clinical, histopathologic, and genomic features of Spitz tumors with ALK fusions. | 30 |
| 24736082 | 2014 | A novel fusion of TPR and ALK in lung adenocarcinoma. | 0 |
| 11888936 | 2002 | Nucleophosmin-anaplastic lymphoma kinase (NPM-ALK), a novel Hsp90-client tyrosine kinase: down-regulation of NPM-ALK expression and tyrosine phosphorylation in ALK(+) CD30(+) lymphoma cells by the Hsp90 antagonist 17-allylamino,17-demethoxygeldanamycin. | 0 |
| 9500471 | 1998 | Nucleolar localization of the nucleophosmin-anaplastic lymphoma kinase is not required for malignant transformation. | 0 |
Article Bibliography
| Pubmed ID | Last Year | Title | Authors |
|---|---|---|---|
| 24736082 | 2014 | A novel fusion of TPR and ALK in lung adenocarcinoma. | Choi YL et al |
Citation
Jean-Loup Huret ; Philippe Dessen
t(1;2)(q31;p23) TPR/ALK
Atlas Genet Cytogenet Oncol Haematol. 0000-00-00
Online version: http://atlasgeneticsoncology.org/solid-tumor/104316/cancer-prone-explorer/haematological-explorer/calendar
