(Note: the fusion was discovered by NGS. Many chromosome rearrangement mechanisms such as translocation, inversion,deletion or complex rearrangement may lead to the same fusion)
Note
Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to u00a0How to contribute
Summary
Note
Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to How to contribute
if you are an author who wish to write a full paper/card on this translocation,go to How to contribute
Highly cited references
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37153035 | 2023 | Inflammatory myofibroblastic tumor of the urinary bladder with FN1‑ALK gene fusion: A case report. | 25 |
| 39280126 | 2024 | Urachal inflammatory myofibroblastic tumor with FN1: : ALK fusion: A case report and literature review. | 19 |
| 34248545 | 2021 | Uterine Leiomyosarcoma with FN1-Anaplastic Lymphoma Kinase Fusion Responsive to Alectinib and Lorlatinib. | 15 |
| 27469327 | 2016 | Recurrent fusion of the genes FN1 and ALK in gastrointestinal leiomyomas. | 0 |
| 32908253 | 2021 | Pseudosarcomatous myofibroblastic proliferations of the urinary bladder are neoplasms characterized by recurrent FN1-ALK fusions. | 0 |
| 25682942 | 2015 | FN1: a novel fusion partner of ALK in an inflammatory myofibroblastic tumor. | 0 |
| 36635892 | 2023 | Pediatric inflammatory myofibroblastic tumor of the bladder with ALK-FN1 fusion successfully treated by alectinib. | 0 |
| 33007314 | 2020 | Inflammatory Myofibroblastic Tumor of the Bladder With FN1-ALK Gene Fusion: Different Response to ALK Inhibition. | 0 |
| 28490045 | 2017 | Uterine Inflammatory Myofibroblastic Tumors Frequently Harbor ALK Fusions With IGFBP5 and THBS1. | 0 |
| 22570254 | 2012 | Identification of anaplastic lymphoma kinase as a potential therapeutic target in ovarian cancer. | 0 |
Article Bibliography
| Pubmed ID | Last Year | Title | Authors |
|---|---|---|---|
| 24875859 | 2014 | Inflammatory myofibroblastic tumors harbor multiple potentially actionable kinase fusions. | Lovly CM et al |
| 25682942 | 2015 | FN1: a novel fusion partner of ALK in an inflammatory myofibroblastic tumor. | Ouchi K et al |
Citation
Jean-Loup Huret ; Philippe Dessen
t(2;2)(p23;q35) FN1/ALK
Atlas Genet Cytogenet Oncol Haematol. 0000-00-00
Online version: http://atlasgeneticsoncology.org/solid-tumor/105220/new-content/pdf
