t(3;22)(q21;q12) EWSR1/KLF15

0000-00-00   Jean-Loup Huret  , Philippe Dessen  

(Note: the fusion was discovered by NGS. Many chromosome rearrangement mechanisms such as translocation, inversion,deletion or complex rearrangement may lead to the same fusion)

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to u00a0How to contribute

Summary

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to  How to contribute

Genes Involved and Proteins

Gene name

Location

22q12.2

Gene name

Location

3q21.3

Highly cited references

Pubmed IDYearTitleCitations
365775252022Whole-genome characterization of myoepithelial carcinomas of the soft tissue.43
337349152021Myoepithelial Carcinoma of Soft Tissue With an EWSR1-KLF15 Gene Fusion in an Infant.17
389246172024Complete remission of EWSR1-KLF15 myoepithelial carcinoma of the soft tissue following pazopanib monotherapy.0
293909272018Malignant Ewing-Like Neoplasm With an EWSR1-KLF15 Fusion: At the Crossroads of a Myoepithelial Carcinoma and a Ewing-Like Sarcoma. A Case Report With Treatment Options.0
265235412016Expanding the Spectrum of Renal Tumors in Children: Primary Renal Myoepithelial Carcinomas With a Novel EWSR1-KLF15 Fusion.0
396363062024Reappraisal of soft tissue myoepithelial tumors by DNA methylation profiling reveals an epigenetically distinct group of mostly fusion-driven neoplasms.0
400210722025Intracardiac myoepithelial carcinoma with EWSR1::KLF15 fusion: a rare case of pediatric primary cardiac malignancy.0

Article Bibliography

Pubmed IDLast YearTitleAuthors
265235412016Expanding the Spectrum of Renal Tumors in Children: Primary Renal Myoepithelial Carcinomas With a Novel EWSR1-KLF15 Fusion.Cajaiba MM et al

Citation

Jean-Loup Huret ; Philippe Dessen

t(3;22)(q21;q12) EWSR1/KLF15

Atlas Genet Cytogenet Oncol Haematol. 0000-00-00

Online version: http://atlasgeneticsoncology.org/solid-tumor/105722/haematological-explorer/case-report-explorer/gene-fusions-explorer/