(Note: the fusion was discovered by NGS. Many chromosome rearrangement mechanisms such as translocation, inversion,deletion or complex rearrangement may lead to the same fusion)
Note
Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to u00a0How to contribute
Summary
Note
Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to How to contribute
if you are an author who wish to write a full paper/card on this translocation,go to How to contribute
Highly cited references
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 28806393 | 2017 | CRAF gene fusions in pediatric low-grade gliomas define a distinct drug response based on dimerization profiles. | 55 |
| 33948563 | 2021 | Clinical utility of comprehensive genomic profiling in central nervous system tumors of children and young adults. | 42 |
| 28912153 | 2017 | Comprehensive Genomic Profiling of 282 Pediatric Low- and High-Grade Gliomas Reveals Genomic Drivers, Tumor Mutational Burden, and Hypermutation Signatures. | 33 |
| 35050712 | 2022 | Sustained Response to the Mitogen-Activated Extracellular Kinase Inhibitor Trametinib in a Spindle Cell Sarcoma Harboring a QKI-RAF1 Gene Fusion. | 15 |
| 30517658 | 2019 | Spinal Pleomorphic Xanthoastrocytoma With a QKI-RAF1 Fusion. | 0 |
Article Bibliography
| Pubmed ID | Last Year | Title | Authors |
|---|---|---|---|
| 23583981 | 2013 | Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas. | Zhang J et al |
| 28806393 | 2017 | CRAF gene fusions in pediatric low-grade gliomas define a distinct drug response based on dimerization profiles. | Jain P et al |
Citation
Jean-Loup Huret ; Philippe Dessen
t(3;6)(p25;q26) QKI/RAF1
Atlas Genet Cytogenet Oncol Haematol. 0000-00-00
Online version: http://atlasgeneticsoncology.org/solid-tumor/106146/meetings/new-content/case-report-explorer/teaching-explorer/
