(Note: the fusion was discovered by NGS. Many chromosome rearrangement mechanisms such as translocation, inversion,deletion or complex rearrangement may lead to the same fusion)
Note
Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to u00a0How to contribute
Summary
Note
Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to How to contribute
if you are an author who wish to write a full paper/card on this translocation,go to How to contribute
Highly cited references
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31164957 | 2019 | Detection of fusion transcripts in the serum samples of patients with hepatocellular carcinoma. | 49 |
| 38537933 | 2024 | Serum Fusion Transcripts to Assess the Risk of Hepatocellular Carcinoma and the Impact of Cancer Treatment through Machine Learning. | 38 |
| 28245430 | 2017 | MAN2A1-FER Fusion Gene Is Expressed by Human Liver and Other Tumor Types and Has Oncogenic Activity in Mice. | 33 |
| 34417538 | 2021 | Detection of fusion gene transcripts in the blood samples of prostate cancer patients. | 31 |
| 25238935 | 2014 | Novel fusion transcripts associate with progressive prostate cancer. | 30 |
| 28459452 | 2017 | Targeting genomic rearrangements in tumor cells through Cas9-mediated insertion of a suicide gene. | 18 |
| 38141924 | 2024 | The Recurrent Liver MAN2A1-FER Oncoprotein Lacks Kinase Activity: Implications for the Use of Tyrosine Kinase Inhibitors. | 10 |
| 39082961 | 2024 | Immuno-targeting the ectopic phosphorylation sites of PDGFRA generated by MAN2A1-FER fusion in HCC. | 0 |
Article Bibliography
| Pubmed ID | Last Year | Title | Authors |
|---|---|---|---|
| 28245430 | 2017 | MAN2A1-FER Fusion Gene Is Expressed by Human Liver and Other Tumor Types and Has Oncogenic Activity in Mice. | Chen ZH et al |
Citation
Jean-Loup Huret ; Philippe Dessen
MAN2A1/FER (5q21)
Atlas Genet Cytogenet Oncol Haematol. 0000-00-00
Online version: http://atlasgeneticsoncology.org/solid-tumor/106698/man2a1-fer-(5q21)
