(Note: the fusion was discovered by NGS. Many chromosome rearrangement mechanisms such as translocation, inversion,deletion or complex rearrangement may lead to the same fusion)
Note
Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to u00a0How to contribute
Summary
Note
Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to How to contribute
if you are an author who wish to write a full paper/card on this translocation,go to How to contribute
Highly cited references
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37152992 | 2023 | Transcriptomic insights into adenoid cystic carcinoma via RNA sequencing. | 88 |
| 30926674 | 2019 | Clinically Integrated Molecular Diagnostics in Adenoid Cystic Carcinoma. | 83 |
| 33878706 | 2021 | SalvGlandDx - a comprehensive salivary gland neoplasm specific next generation sequencing panel to facilitate diagnosis and identify therapeutic targets. | 73 |
| 29610392 | 2018 | Personalized oncogenomic analysis of metastatic adenoid cystic carcinoma: using whole-genome sequencing to inform clinical decision-making. | 55 |
| 33791153 | 2021 | Establishment of patient-derived xenograft models of adenoid cystic carcinoma to assess pre-clinical efficacy of combination therapy of a PI3K inhibitor and retinoic acid. | 43 |
| 39760648 | 2025 | Molecular Profiling of Sinonasal Adenoid Cystic Carcinoma: Canonical and Noncanonical Gene Fusions and Mutation. | 41 |
| 36077692 | 2022 | Identification of Fusion Genes and Targets for Genetically Matched Therapies in a Large Cohort of Salivary Gland Cancer Patients. | 40 |
| 38896376 | 2024 | A Novel Scoring System for MYB RNA In Situ Hybridization Displays High Sensitivity and Specificity for Adenoid Cystic Carcinoma in a Clinical Setting. | 40 |
| 29149504 | 2018 | MYBL1 rearrangements and MYB amplification in breast adenoid cystic carcinomas lacking the MYB-NFIB fusion gene. | 38 |
| 39508931 | 2024 | Targeted RNA Sequencing of Head and Neck Adenoid Cystic Carcinoma Reveals SEC16A::NOTCH1 Fusion and MET Exon 14 Skipping as Potentially Actionable Alterations. | 38 |
| 31028361 | 2019 | Detecting MYB and MYBL1 fusion genes in tracheobronchial adenoid cystic carcinoma by targeted RNA-sequencing. | 28 |
| 39235305 | 2024 | Discovery of Novel TULP4/ACTN4/EWSR1/ACTB::MYB and ESRRG::DNM3 Fusions Expands Molecular Landscape of Adenoid Cystic Carcinoma Beyond Fusions Between MYB/MYBL1 and NFIB Genes. | 27 |
| 26631609 | 2016 | Novel MYBL1 Gene Rearrangements with Recurrent MYBL1-NFIB Fusions in Salivary Adenoid Cystic Carcinomas Lacking t(6;9) Translocations. | 26 |
| 30962747 | 2019 | Possible Relationship Between MYBL1 Alterations and Specific Primary Sites in Adenoid Cystic Carcinoma: A Clinicopathological and Molecular Study of 36 Cases. | 25 |
| 33405400 | 2021 | Molecular Pathology of Salivary Gland Neoplasms: Diagnostic, Prognostic, and Predictive Perspective. | 0 |
| 37423587 | 2023 | The Landscape of MYB/MYBL1- and Peri-MYB/MYBL1-Associated Rearrangements in Adenoid Cystic Carcinoma. | 0 |
| 28594149 | 2017 | MYB, MYBL1, MYBL2 and NFIB gene alterations and MYC overexpression in salivary gland adenoid cystic carcinoma. | 0 |
| 29410490 | 2018 | MYB and MYBL1 in adenoid cystic carcinoma: diversity in the mode of genomic rearrangement and transcripts. | 0 |
| 29570128 | 2018 | Small Subset of Adenoid Cystic Carcinoma of the Skin Is Associated With Alterations of the MYBL1 Gene Similar to Their Extracutaneous Counterparts. | 0 |
| 34413003 | 2021 | Detection of novel fusion genes by next-generation sequencing-based targeted RNA sequencing analysis in adenoid cystic carcinoma of head and neck. | 0 |
| 35267084 | 2022 | The evolving role of molecular pathology in the diagnosis of salivary gland tumours with potential pitfalls. | 0 |
| 37706251 | 2023 | Molecular characterisation of tumours of the lacrimal apparatus. | 0 |
| 36920022 | 2023 | Adenoid Cystic Carcinoma With Striking Tubular Hypereosinophilia: A Unique Pattern Associated With Nonparotid Location and Both Canonical and Novel EWSR1::MYB and FUS::MYB Fusions. | 0 |
| 29619555 | 2018 | Prognostic significance of 1p36 locus deletion in adenoid cystic carcinoma of the salivary glands. | 0 |
| 34864773 | 2022 | Metatypical Adenoid Cystic Carcinoma: A Variant Showing Prominent Squamous Differentiation With a Predilection for the Sinonasal Tract and Skull Base. | 0 |
| 37792636 | 2024 | Cell-type-specific tumour sensitivity identified with a bromodomain targeting PROTAC in adenoid cystic carcinoma. | 0 |
Article Bibliography
| Pubmed ID | Last Year | Title | Authors |
|---|---|---|---|
| 26631070 | 2016 | Recurrent Fusions in MYB and MYBL1 Define a Common, Transcription Factor-Driven Oncogenic Pathway in Salivary Gland Adenoid Cystic Carcinoma. | Brayer KJ et al |
| 26631609 | 2016 | Novel MYBL1 Gene Rearrangements with Recurrent MYBL1-NFIB Fusions in Salivary Adenoid Cystic Carcinomas Lacking t(6;9) Translocations. | Mitani Y et al |
| 26862087 | 2016 | Whole-Genome Sequencing of Salivary Gland Adenoid Cystic Carcinoma. | Rettig EM et al |
Citation
Jean-Loup Huret ; Philippe Dessen
t(8;9)(q13;p22) MYBL1/NFIB
Atlas Genet Cytogenet Oncol Haematol. 0000-00-00
Online version: http://atlasgeneticsoncology.org/solid-tumor/108253/t(8
