t(X;22)(p22;q12) EWSR1/BEND2

0000-00-00   Jean-Loup Huret  , Philippe Dessen  

(Note: the fusion was discovered by NGS. Many chromosome rearrangement mechanisms such as translocation, inversion,deletion or complex rearrangement may lead to the same fusion)

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to u00a0How to contribute

Summary

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to  How to contribute

Genes Involved and Proteins

Gene name

Location

22q12.2

Gene name

Location

Xp22.13

Highly cited references

Pubmed IDYearTitleCitations
366043862023Early ependymal tumor with MN1-BEND2 fusion: a mostly cerebral tumor of female children with a good prognosis that is distinct from classical astroblastoma.84
383390142024Identification of Novel/Rare EWSR1 Fusion Partners in Undifferentiated Mesenchymal Neoplasms.56
366908052023Gene fusions are frequent in ACTH-secreting neuroendocrine neoplasms of the pancreas, but not in their non-pancreatic counterparts.44
391041572024Spinal Cord Astroblastoma With EWSR1-BEND2 Fusion in Female Patients : A Report of Four Cases From China and a Comprehensive Literature Review.43
394953742024Malignant Salivary Gland Neoplasm of the Tongue Base with EWSR1::BEND2 Fusion: An Unusual Case with Literature Review.43
394276442024Long-Term Follow-Up of a Child with EWSR1-BEND2 Fused Spinal Astroblastoma.34
321244192020Salivary Gland Cancer in the Era of Routine Next-Generation Sequencing.32
366469852023A Low-grade Sinonasal Sarcoma Harboring EWSR1::BEND2: Expanding the Differential Diagnosis of Sinonasal Spindle Cell Neoplasms.22
395291802024A primary intracranial neuroepithelial neoplasm with novel TCF3::BEND2 fusion: a case report.18
372846242021Molecular clarification of brainstem astroblastoma with EWSR1-BEND2 fusion in a 38-year-old man.16
348252672022EWSR1-BEND2 fusion defines an epigenetically distinct subtype of astroblastoma.14
397751862025EWSR1::BEND2 Adenocarcinoma with Hyaline Pseudorosettes of the Trachea.5
343138812021Spinal cord astroblastoma with EWSR1-BEND2 fusion classified as HGNET-MN1 by methylation classification: a case report.0
353017442022Paediatric astroblastoma-like neuroepithelial tumour of the spinal cord with a MAMLD1-BEND2 rearrangement.0
318634782020Spinal cord astroblastoma with an EWSR1-BEND2 fusion classified as a high-grade neuroepithelial tumour with MN1 alteration.0
388571912024Astroblastoma With a Novel YAP1::BEND2 Fusion: A Case Report.0

Article Bibliography

Pubmed IDLast YearTitleAuthors
281993142017Whole-genome landscape of pancreatic neuroendocrine tumours.Scarpa A et al

Citation

Jean-Loup Huret ; Philippe Dessen

t(X;22)(p22;q12) EWSR1/BEND2

Atlas Genet Cytogenet Oncol Haematol. 0000-00-00

Online version: http://atlasgeneticsoncology.org/solid-tumor/108685/gene-fusions-explorer/meetings/submit-meetings/