Mesenchymal tumors

2022-12-01   Paola Dal Cin, PhD , Michelle S. Hirsch, MD 

1.Brigham and Women's Hospital , Harvard Medical School, Boston , MA (USA)

Classification

Definition

Tumors that typically arise in soft tissue are being identified with increasing frequency in the genitourinary system, and this is aided by molecular tools. Some lesions that are most relevant to the urinary tract, and can be difficult to diagnose, include Ewing sarcoma of the urinary tract particularly in the kidney, 1 and inflammatory myofibroblastic tumors in the urinary bladder.2,3 Genetic confirmations remain essential for exclusion or confirmation when benign lesions and sarcomas are identified resembling those typically found in soft tissues.  Therefore, more comprehensive details will be available in the WHO 2020 Soft Tissue and Bone Tumours 

Article Bibliography

Reference NumberPubmed IDLast YearTitleAuthors
1290459812017Renal Ewing's sarcoma/primitive neuroectodermal tumor: a case report and literature review.Liu C et al
2329082532021Pseudosarcomatous myofibroblastic proliferations of the urinary bladder are neoplasms characterized by recurrent FN1-ALK fusions.Acosta AM et al
3326457602020TERT promoter mutation analysis as a surrogate to morphology and immunohistochemistry in problematic spindle cell lesions of the urinary bladder.Bertz S et al

Citation

Paola Dal Cin, PhD ; Michelle S. Hirsch, MD

Mesenchymal tumors

Atlas Genet Cytogenet Oncol Haematol. 2022-12-01

Online version: http://atlasgeneticsoncology.org/solid-tumor/208972/mesenchymal-tumors