EBV-positive lymphoproliferative diseases of childhood

2023-05-14   Sheng Xiao, MD , Chunxiao Yang  

1.Brigham and Women's Hospital

Classification

Definition

EBV-positive lymphoproliferative diseases of childhoodGenetic marker(s)
Systemic EBV-positive T-cell lymphoma of childhoodSystemic EBV-positive T-cell lymphoma of childhood is a rapidly progressing disease characterized by multiorgan failure, sepsis, and ultimately death and is caused by the clonal proliferation of T cells infected with the EBV. There are currently no consistent chromosome or gene alterations that have been identified in association with this disease.
Hydroa vacciniforme lymphoproliferative disorderNo consistent chromosome/gene alterations are described. TCR is usually clonal but does not correlate with the severity of the disease.

Bibliography

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Citation

Sheng Xiao, MD ; Chunxiao Yang

EBV-positive lymphoproliferative diseases of childhood

Atlas Genet Cytogenet Oncol Haematol. 2023-05-14

Online version: http://atlasgeneticsoncology.org/solid-tumor/209157/ebv-positive-lymphoproliferative-diseases-of-childhood