EBV-positive lymphoproliferative diseases of childhood
2023-05-14 Sheng Xiao, MD , Chunxiao Yang   Affiliation1.Brigham and Women's Hospital
Classification
Definition
| EBV-positive lymphoproliferative diseases of childhood | Genetic marker(s) | |
|---|---|---|
| Systemic EBV-positive T-cell lymphoma of childhood | Systemic EBV-positive T-cell lymphoma of childhood is a rapidly progressing disease characterized by multiorgan failure, sepsis, and ultimately death and is caused by the clonal proliferation of T cells infected with the EBV. There are currently no consistent chromosome or gene alterations that have been identified in association with this disease. | |
| Hydroa vacciniforme lymphoproliferative disorder | No consistent chromosome/gene alterations are described. TCR is usually clonal but does not correlate with the severity of the disease. |
Bibliography
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Citation
Sheng Xiao, MD ; Chunxiao Yang
EBV-positive lymphoproliferative diseases of childhood
Atlas Genet Cytogenet Oncol Haematol. 2023-05-14
Online version: http://atlasgeneticsoncology.org/solid-tumor/209157/ebv-positive-lymphoproliferative-diseases-of-childhood
