The head and neck region is the second most common site of origin for extranodal lymphomas (following the gastrointestinal tract). Involvement by myeloid sarcoma and histiocytic/dendritic neoplasms is rare. Cervical lymph nodes are a common site for involvement by lymphoma. Waldeyer’s ring is the most common extranodal primary site for non-Hodgkin lymphoma within the head and neck.¹ Other relatively common primary sites for lymphoma include salivary glands and ocular adnexa, while primary lymphomas of the thyroid and sinonasal tract are uncommon and primary lymphomas of the oral cavity and larynx are rare. ^2-5 Throughout the head and neck, B-cell lymphomas are much more common than T-cell or NK-cell lymphomas; an important exception is the nasal cavity, which is the most common site of origin for extranodal NK/T-cell lymphoma.⁵ While there is some overlap in histologic and immunophenotypic features between extranodal and nodal lymphomas, there are important differences. For example, Hodgkin lymphoma is rare in extranodal sites, while extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) and extranodal NK/T-cell lymphoma (ENKTL) by definition arise in extranodal sites, and plasmablastic lymphoma is extranodal in the vast majority of cases. In addition, pediatric-type follicular lymphoma (PTFL) most commonly arises in cervical lymph nodes⁶ while large B-cell lymphoma with IRF4 rearrangement (LBCL-IRF4) most often arises in Waldeyer’s ring.⁷ Detailed information on lymphomas encountered in the head and neck is available in the WHO 2022 Classification of Tumours of Haematopoietic and Lymphoid tissues.