Odontogenic and maxillofacial bone tumors
2025-11-23 Paola Dal Cin, PhD Affiliation1.Brigham and Women's Hospital , Harvard Medical School, Boston , MA (USA)
Classification
Definition
Odontogenic and Maxillofacial Bone Tumors encompass cysts of the jaws, odontogenic tumors, giant cell lesions and bone cysts, and bone and cartilage tumors.
The molecular findings in odontogenic cysts and tumors play a significant role in pathogenesis, but at least for now, none are defining characteristics. 1,2
The CTNNB1/Wnt aberrations are shared with other head and neck, ghost cell-containing tumors, both non-odontogenic (i.e., adamantinomatous craniopharyngioma and pilomatrixoma) and odontogenic (dentinogenic ghost cell tumour, ghost cell odontogenic carcinoma.
Article Bibliography
| Reference Number | Pubmed ID | Last Year | Title | Authors |
|---|---|---|---|---|
| 1 | 3183586 | 1988 | Culture of newt cells from different tissues and their expression of a regeneration-associated antigen. | Ferretti P et al |
| 2 | 35312978 | 2022 | Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Odontogenic and Maxillofacial Bone Tumours. | Vered M et al |
Citation
Paola Dal Cin, PhD
Odontogenic and maxillofacial bone tumors
Atlas Genet Cytogenet Oncol Haematol. 2025-11-23
Online version: http://atlasgeneticsoncology.org/solid-tumor/209343/odontogenic-and-maxillofacial-bone-tumors
