1.Laboratory for Tumor Biology, Developmental Disorders, University Hospital Eppendorf, Martinistr. 52, 20246 Hamburg, Germany.
Results of surgery of PNF are usually unsatisfactory because of the network-like growth of the tumors often involve multiple nerve fascicles and other adjacent tissues. Typically surgical interventions for PNF are restricted to debulking procedures of large tumors causing significant clinical complications or aesthetic disfigurement. However, successful subtotal resections of the superficial PNF with significant improvement in cosmetic appearance are possible. Furthermore, a recent study reported the advantage of early surgical intervention of small PNF in children under 15 years of age. Total resection was achieved in all 7 cases without causing any neurological or organic deficit. Annual control within four years with magnetic resonance tomography did not reveal any relapse of the tumors.
Lan Kluwe ; Christian Hagel ; Victor Mautner
Nervous System: Neurofibroma
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/solid-tumor/5098/nervous-system-neurofibroma