CLEC10A (C-type lectin domain containing 10A)

2003-06-01  

Identity

HGNC
LOCATION
17p13.1
LOCUSID
ALIAS
CD301,CLECSF13,CLECSF14,HML,HML2,MGL

Other Information

Locus ID:

NCBI: 10462
MIM: 605999
HGNC: 16916
Ensembl: ENSG00000132514

Variants:

dbSNP: 10462
ClinVar: 10462
TCGA: ENSG00000132514
COSMIC: CLEC10A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000132514ENST00000254868Q8IUN9
ENSG00000132514ENST00000416562J3KR22
ENSG00000132514ENST00000571664Q8IUN9
ENSG00000132514ENST00000576549I3NI09
ENSG00000132514ENST00000576617Q8IUN9

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
C-type lectin receptors (CLRs)REACTOMER-HSA-5621481
Dectin-2 familyREACTOMER-HSA-5621480

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
350937312022High expression of CLEC10A in head and neck squamous cell carcinoma indicates favorable prognosis and high-level immune infiltration status.1
350937312022High expression of CLEC10A in head and neck squamous cell carcinoma indicates favorable prognosis and high-level immune infiltration status.1
319112412020Characterization of Macrophage Galactose-type Lectin (MGL) ligands in colorectal cancer cell lines.17
327522592020N-Glycoproteins Have a Major Role in MGL Binding to Colorectal Cancer Cell Lines: Associations with Overall Proteome Diversity.6
319112412020Characterization of Macrophage Galactose-type Lectin (MGL) ligands in colorectal cancer cell lines.17
327522592020N-Glycoproteins Have a Major Role in MGL Binding to Colorectal Cancer Cell Lines: Associations with Overall Proteome Diversity.6
305826982019Glycoproteomic Analysis of MGL-Binding Proteins on Acute T-Cell Leukemia Cells.10
312196602019The C-type lectin receptor MGL senses N-acetylgalactosamine on the unique Staphylococcus aureus ST395 wall teichoic acid.12
305826982019Glycoproteomic Analysis of MGL-Binding Proteins on Acute T-Cell Leukemia Cells.10
312196602019The C-type lectin receptor MGL senses N-acetylgalactosamine on the unique Staphylococcus aureus ST395 wall teichoic acid.12
297554532018CLEC10A Is a Specific Marker for Human CD1c(+) Dendritic Cells and Enhances Their Toll-Like Receptor 7/8-Induced Cytokine Secretion.59
297554532018CLEC10A Is a Specific Marker for Human CD1c(+) Dendritic Cells and Enhances Their Toll-Like Receptor 7/8-Induced Cytokine Secretion.59
277068072017Intermediate monocytes are increased in enthesitis-related arthritis, a category of juvenile idiopathic arthritis.13
277068072017Intermediate monocytes are increased in enthesitis-related arthritis, a category of juvenile idiopathic arthritis.13
261479702015The Macrophage Galactose-Type C-Type Lectin (MGL) Modulates Regulatory T Cell Functions.12

Citation

Dessen P

CLEC10A (C-type lectin domain containing 10A)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/40100/favicon/hgnc