CTSE (cathepsin E)

2003-06-01 Affiliation

Identity

HGNC

CTSE

LOCATION

1q32.1

LOCUSID

1510

ALIAS

CATE

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 1510
MIM: 116890
HGNC: 2530
Ensembl: ENSG00000196188

Variants:

dbSNP: 1510
ClinVar: 1510
TCGA: ENSG00000196188
COSMIC: CTSE

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000196188	ENST00000358184	P14091
ENSG00000196188	ENST00000360218	P14091

Expression (GTEx)

100

150

200

250

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Lysosome	KEGG	ko04142
Lysosome	KEGG	hsa04142
Immune System	REACTOME	R-HSA-168256
Adaptive Immune System	REACTOME	R-HSA-1280218
MHC class II antigen presentation	REACTOME	R-HSA-2132295

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
35181976	2022	Microglial cathepsin E plays a role in neuroinflammation and amyloid β production in Alzheimer's disease.	9
35181976	2022	Microglial cathepsin E plays a role in neuroinflammation and amyloid β production in Alzheimer's disease.	9
30278264	2019	The Relationship between the Concentration of Cathepsin A, D, and E and the Concentration of Copper and Zinc, and the Size of the Aneurysmal Enlargement in the Wall of the Abdominal Aortic Aneurysm.	7
30278264	2019	The Relationship between the Concentration of Cathepsin A, D, and E and the Concentration of Copper and Zinc, and the Size of the Aneurysmal Enlargement in the Wall of the Abdominal Aortic Aneurysm.	7
25348778	2015	High Expression of Cathepsin E in Tissues but Not Blood of Patients with Barrett's Esophagus and Adenocarcinoma.	10
25348778	2015	High Expression of Cathepsin E in Tissues but Not Blood of Patients with Barrett's Esophagus and Adenocarcinoma.	10
24242330	2014	Repression of cathepsin E expression increases the risk of mammary carcinogenesis and links to poor prognosis in breast cancer.	13
24464956	2014	Role of cathepsin E in decidual macrophage of patients with recurrent miscarriage.	10
25239563	2014	Cathepsin E promotes pulmonary emphysema via mitochondrial fission.	19
24242330	2014	Repression of cathepsin E expression increases the risk of mammary carcinogenesis and links to poor prognosis in breast cancer.	13
24464956	2014	Role of cathepsin E in decidual macrophage of patients with recurrent miscarriage.	10
25239563	2014	Cathepsin E promotes pulmonary emphysema via mitochondrial fission.	19
23451082	2013	Cathepsin E is a marker of gastric differentiation and signet-ring cell carcinoma of stomach: a novel suggestion on gastric tumorigenesis.	24
23451082	2013	Cathepsin E is a marker of gastric differentiation and signet-ring cell carcinoma of stomach: a novel suggestion on gastric tumorigenesis.	24
21664991	2012	Emerging roles of cathepsin E in host defense mechanisms.	15

Citation

Dessen P

CTSE (cathepsin E)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/40204/gene-fusions-explorer/hgnc