ADGRL4 (adhesion G protein-coupled receptor L4)

2013-11-01  

Identity

HGNC
ADGRL4
LOCATION
1p31.1
LOCUSID
64123
ALIAS
ELTD1,ETL,KPG_003

Other Information

Locus ID:

NCBI: 64123
MIM: 616419
HGNC: 20822
Ensembl: ENSG00000162618

Variants:

dbSNP: 64123
ClinVar: 64123
TCGA: ENSG00000162618
COSMIC: ADGRL4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000162618ENST00000370742Q9HBW9
ENSG00000162618ENST00000401034B1AR72
ENSG00000162618ENST00000640664A0A1W2PP07
ENSG00000162618ENST00000655029A0A590UJX8
ENSG00000162618ENST00000656300A0A590UJ41
ENSG00000162618ENST00000656841A0A590UJX8
ENSG00000162618ENST00000659463A0A590UJS7
ENSG00000162618ENST00000661030A0A590UJX8
ENSG00000162618ENST00000662530A0A590UK74
ENSG00000162618ENST00000662640A0A590UK90
ENSG00000162618ENST00000662895A0A590UJU5
ENSG00000162618ENST00000671209A0A590UJN9

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
238716372013A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesis.71
230964112013ELTD1, a potential new biomarker for gliomas.33
185198292008An autosomal linkage scan for cannabis use disorders in the nicotine addiction genetics project.28
264494642015MicroRNA-139-5p acts as a tumor suppressor by targeting ELTD1 and regulating cell cycle in glioblastoma multiforme.15
274169552017ELTD1, an effective anti-angiogenic target for gliomas: preclinical assessment in mouse GL261 and human G55 xenograft glioma models.11
234745352013Microsatellite scanning of the immunogenome associates MAPK14 and ELTD1 with graft-versus-host disease in hematopoietic stem cell transplantation.4

Citation

Dessen P

ADGRL4 (adhesion G protein-coupled receptor L4)

Atlas Genet Cytogenet Oncol Haematol. 2013-11-01

Online version: http://atlasgeneticsoncology.org/gene/53620/adgrl4-(adhesion-g-protein-coupled-receptor-l4)