It is known that human endogenous retroviruses (ERVs) and ERV-like sequences are part of the repetitive portions of the human genome and are remnants of infections of former exogenous retroviruses. They comprise approximately 8% of the human genome (Landers et al, 2001) and include solitary long terminal repeats (LTRs), non-retroviral sequences flanked by LTRs, and LTRs-like sequences (Mayer et al, 2011). ERVs are divided into various groups.
Endogenous retrovirus group H member 1 (ERVH-1), formerly HERV-H4p15.2, is an integrated retroviral element of the human genome and maps on Chromosome 4, in particular on 4p15.2

Usually, human ERVs are silenced epigenetically and are not transcribed (Kewitz and Staege, 2013), however, they are found to be transcribed in particular situations, such as under pathological conditions, and usually their transcription is initiated by promoter sequences within the proviral LTRs (Mayer et al, 2011).
ERVH-1 gene produces a long non-coding RNA (LncRNA), named ERVH-1-201, of 639 nt. Its sequence is registered in GenBank (BC015108 or EU669866) and in Ensembl (ENSG00000251292). The tissue of origin in which it was first identified is renal cell carcinoma (hypernephroma) (Liang et al, 2009), but it has been detected in various human tissues (see figure 1) and preferentially in human embryonic stem cells (hESCs) (Lu et al, 2014).

The subcellular localization of ERVH-1 is almost-exclusive to the nucleus (Lu et al, 2014).

No pseudogenes were observed for the ERVH-1 sequence.

It is well-known that human ERVs and ERV-like sequences no longer encode proteins because of the accumulation of nonsense mutations as a consequence of their ancient incorporation into the genome of the host (Mayer et al, 2011). For ERVH-1 no protein has been identified so far.