ADGRG3 (adhesion G protein-coupled receptor G3)

2015-06-01  

Identity

HGNC
LOCATION
16q21
LOCUSID
ALIAS
GPR97,PB99,PGR26
FUSION GENES

Other Information

Locus ID:

NCBI: 222487
MIM: 618441
HGNC: 13728
Ensembl: ENSG00000182885

Variants:

dbSNP: 222487
ClinVar: 222487
TCGA: ENSG00000182885
COSMIC: ADGRG3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000182885ENST00000333493Q86Y34
ENSG00000182885ENST00000450388F8W8F7
ENSG00000182885ENST00000567991H3BRU4
ENSG00000182885ENST00000568245H3BS78

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450
500

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
241782982013The orphan adhesion G protein-coupled receptor GPR97 regulates migration of lymphatic endothelial cells via the small GTPases RhoA and Cdc42.18
305597452018The Adhesion G Protein-Coupled Receptor GPR97/ADGRG3 Is Expressed in Human Granulocytes and Triggers Antimicrobial Effector Functions.1
204244732010L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.0

Citation

Dessen P

ADGRG3 (adhesion G protein-coupled receptor G3)

Atlas Genet Cytogenet Oncol Haematol. 2015-06-01

Online version: http://atlasgeneticsoncology.org/gene/76595/adgrg3-(adhesion-g-protein-coupled-receptor-g3)